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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
(Rule 13d-102)
Under the Securities Exchange Act of 1934
(Amendment No. _)*
LEXICON PHARMACEUTICALS, INC.
(Name of Issuer)
COMMON STOCK, PAR VALUE $0.001 PER SHARE
(Title of Class of Securities)
528872104
(CUSIP Number)
JUNE 15, 2007
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:
[_] Rule 13d-1(b)
[X] Rule 13d-1(c)
[_] Rule 13d-1(d)
*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.
The information required on the reminder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).
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CUSIP No. 528872104 Page 2 of 20
Schedule 13G
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1 NAMES OF REPORTING PERSON
S.S OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Symphony Capital Partners, L.P.
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2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(SEE INSTRUCTIONS) (a) [_]
(b) [X]
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3 SEC USE ONLY
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4 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
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5 SOLE VOTING POWER
NUMBER OF 4,954,745
-------------------------------------------
SHARES BENEFICIALLY 6 SHARED VOTING POWER
OWNED BY -0-
-------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING PERSON 4,954,745
-------------------------------------------
8 SHARED DISPOSITIVE POWER
-0-
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9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
4,954,745
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10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES (SEE INSTRUCTIONS)
[_]
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11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
5.8%
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12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
PN
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CUSIP No. 528872104 Page 3 of 20
Schedule 13G
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1 NAMES OF REPORTING PERSON
S.S OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Symphony Capital GP, L.P.
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2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(SEE INSTRUCTIONS) (a) [_]
(b) [X]
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3 SEC USE ONLY
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4 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
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5 SOLE VOTING POWER
NUMBER OF 4,954,745
-------------------------------------------
SHARES BENEFICIALLY 6 SHARED VOTING POWER
OWNED BY -0-
-------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING PERSON 4,954,745
-------------------------------------------
8 SHARED DISPOSITIVE POWER
-0-
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9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
4,954,745
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10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES (SEE INSTRUCTIONS)
[_]
--------------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
5.8%
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12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
PN
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CUSIP No. 528872104 Page 4 of 20
Schedule 13G
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1 NAMES OF REPORTING PERSON
S.S OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Symphony GP, LLC
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2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(SEE INSTRUCTIONS) (a) [_]
(b) [X]
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3 SEC USE ONLY
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4 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
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5 SOLE VOTING POWER
NUMBER OF 4,954,745
-------------------------------------------
SHARES BENEFICIALLY 6 SHARED VOTING POWER
OWNED BY -0-
-------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING PERSON 4,954,745
-------------------------------------------
8 SHARED DISPOSITIVE POWER
-0-
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9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
4,954,745
--------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES (SEE INSTRUCTIONS)
[_]
--------------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
5.8%
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12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
OO
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CUSIP No. 528872104 Page 5 of 20
Schedule 13G
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1 NAMES OF REPORTING PERSON
S.S OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Symphony Strategic Partners, LLC
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2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(SEE INSTRUCTIONS) (a) [_]
(b) [X]
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3 SEC USE ONLY
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4 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
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5 SOLE VOTING POWER
NUMBER OF 374,869
-------------------------------------------
SHARES BENEFICIALLY 6 SHARED VOTING POWER
OWNED BY -0-
-------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING PERSON 374,869
-------------------------------------------
8 SHARED DISPOSITIVE POWER
-0-
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9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
374,869
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10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES (SEE INSTRUCTIONS)
[_]
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11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
0.4%
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12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
OO
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CUSIP No. 528872104 Page 6 of 20
Schedule 13G
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1 NAMES OF REPORTING PERSON
S.S OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Mark Kessel
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2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(SEE INSTRUCTIONS) (a) [_]
(b) [X]
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3 SEC USE ONLY
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4 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
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5 SOLE VOTING POWER
NUMBER OF -0-
-------------------------------------------
SHARES BENEFICIALLY 6 SHARED VOTING POWER
OWNED BY 5,329,614
-------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING PERSON -0-
-------------------------------------------
8 SHARED DISPOSITIVE POWER
5,329,614
--------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
5,329,614
--------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES (SEE INSTRUCTIONS)
[_]
--------------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
6.2%
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12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
IN
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CUSIP No. 528872104 Page 7 of 20
Schedule 13G
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1 NAMES OF REPORTING PERSON
S.S OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Neil J. Sandler
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2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(SEE INSTRUCTIONS) (a) [_]
(b) [X]
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3 SEC USE ONLY
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4 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
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5 SOLE VOTING POWER
NUMBER OF -0-
-------------------------------------------
SHARES BENEFICIALLY 6 SHARED VOTING POWER
OWNED BY 5,329,614
-------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING PERSON -0-
-------------------------------------------
8 SHARED DISPOSITIVE POWER
5,329,614
--------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
5,329,614
--------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES (SEE INSTRUCTIONS)
[_]
--------------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
6.2%
--------------------------------------------------------------------------------
12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
IN
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CUSIP No. 528872104 Page 8 of 20
Schedule 13G
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1 NAMES OF REPORTING PERSON
S.S OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)
Harri V. Taranto
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2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(SEE INSTRUCTIONS) (a) [_]
(b) [X]
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3 SEC USE ONLY
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4 CITIZENSHIP OR PLACE OF ORGANIZATION
United States
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5 SOLE VOTING POWER
NUMBER OF -0-
-------------------------------------------
SHARES BENEFICIALLY 6 SHARED VOTING POWER
OWNED BY 5,329,614
-------------------------------------------
EACH 7 SOLE DISPOSITIVE POWER
REPORTING PERSON -0-
-------------------------------------------
8 SHARED DISPOSITIVE POWER
5,329,614
--------------------------------------------------------------------------------
9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
5,329,614
--------------------------------------------------------------------------------
10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES
CERTAIN SHARES (SEE INSTRUCTIONS)
[_]
--------------------------------------------------------------------------------
11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
6.2%
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12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
IN
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CUSIP No. 528872104 Page 9 of 20
Schedule 13G
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Item 1. (a) NAME OF ISSUER
Lexicon Pharmaceuticals, Inc. (the "Company").
(b) ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES
8800 Technology Forest Place, The Woodlands, Texas 77381
Item 2. (a) NAMES OF PERSONS FILING
This Statement is being filed on behalf of each of the
following persons (collectively, the "Reporting Persons")
(i) Symphony Capital Partners, L.P. ("SCP")
(ii) Symphony Capital GP, L.P. ("Symphony Capital GP")
(iii) Symphony GP, LLC ("Symphony GP")
(iv) Symphony Strategic Partners, LLC ("SSP")
(v) Mark Kessel
(vi) Neil J. Sandler
(vii) Harri V. Taranto
CUSIP No. 528872104 Page 10 of 20
Schedule 13G
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(b) ADDRESS OF PRINCIPAL BUSINESS OFFICE
The address of the principal business offices of the Reporting
Persons is 875 Third Avenue, 18th Floor, New York, NY 10022
(c) CITIZENSHIP
(i) SCP - a Delaware limited partnership
(ii) Symphony Capital GP - a Delaware limited partnership
(iii) Symphony GP - a Delaware limited liability company
(iv) SSP - a Delaware limited liability company
(v) Mark Kessel - a citizen of the United States
(vi) Neil J. Sandler - a citizen of the United States
(vii) Harri V. Taranto - a citizen of the United States
(d) TITLE OF CLASS OF SECURITIES
Common Stock, par value $0.001 per share (the "Common Stock"
or "Shares")
(e) CUSIP NUMBER
528872104
CUSIP No. 528872104 Page 11 of 20
Schedule 13G
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Item 3. This statement is not being filed pursuant to either Rule 13d-1(b) or
13d-2(b) or (c).
Item 4. OWNERSHIP.
(a) AMOUNT BENEFICIALLY OWNED:
(i) Each of SCP, Symphony Capital GP and Symphony GP may
be deemed to beneficially own an aggregate of 4,954,745
Shares.
(ii) SSP may be deemed to beneficially own an aggregate of
374,869 Shares.
(iii) Each of Mark Kessel, Neil J. Sandler and Harri V.
Taranto may be deemed to beneficially own an aggregate of
5,329,614 Shares.
(b) PERCENTAGE OWNED:
Based on calculations made in accordance with Rule 13d-3(d),
and there being 85,961,249 Shares outstanding as of June 15,
2007, (i) each of SCP, Symphony Capital GP and Symphony GP may
be deemed to own approximately 5.8% of the outstanding Common
Stock, (ii) SSP may be deemed to own approximately 0.4% of the
outstanding Common Stock, and (iii) each of Mark Kessel, Neil
J. Sandler and Harri V. Taranto may be deemed to beneficially
own approximately 6.2% of the outstanding Common Stock.
(c) NUMBER OF SHARES AS TO WHICH SUCH PERSON HAS:
(i) Each of SCP, Symphony Capital GP, Symphony GP may be
deemed to have sole power to direct the voting and disposition
of 4,954,745 Shares.
(ii) SSP may be deemed to have sole power to direct the
voting and disposition of 374,869 Shares.
(iii) Each of Mark Kessel, Neil J. Sandler and Harri V.
Taranto may be deemed to have shared power to direct the
voting and disposition of 5,329,614 Shares.
Item 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS
Not applicable.
Item 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON
Not applicable.
CUSIP No. 528872104 Page 12 of 20
Schedule 13G
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Item 7. IDENTIFICATION AND CLASSIFICATION OF SUBSIDIARY WHICH ACQUIRED THE
SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY
Not applicable.
Item 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP
See Item 2.
Item 9. NOTICE OF DISSOLUTION OF GROUP
Not applicable.
Item 10. CERTIFICATION
By signing below I certify that, to the best of my knowledge and
belief, the securities referred to above were not acquired and are
not held for the purpose of or with the effect of changing or
influencing the control of the issuer of the securities and were not
acquired and are not held in connection with or as a participant in
any transaction having that purpose or effect.
[REMAINDER OF PAGE INTENTIONALLY LEFT BLANK]
CUSIP No. 528872104 Page 13 of 20
Schedule 13G
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SIGNATURES
After reasonable inquiry and to the best of our knowledge and
belief, the undersigned certify that the information set forth in this
statement is true, complete and correct.
Dated as of June 25, 2007
SYMPHONY CAPITAL PARTNERS, L.P.
By: Symphony Capital GP, L.P.
its general partner
By: Symphony GP, LLC
its general partner
By: /s/ Mark Kessel
--------------------------------
Name: Mark Kessel
Title: Managing Member
SYMPHONY STRATEGIC PARTNERS, LLC
By: /s/ Mark Kessel
--------------------------------
Name: Mark Kessel
Title: Managing Member
CUSIP No. 528872104 Page 14 of 20
Schedule 13G
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SYMPHONY CAPITAL GP, L.P.
By: Symphony GP, LLC
its general partner
By: /s/ Mark Kessel
--------------------------------
Name: Mark Kessel
Title: Managing Member
SYMPHONY GP, LLC
By: /s/ Mark Kessel
--------------------------------
Name: Mark Kessel
Title: Managing Member
CUSIP No. 528872104 Page 15 of 20
Schedule 13G
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MARK KESSEL
By: /s/ Mark Kessel
--------------------------------
Name: Mark Kessel
Title: Managing Member
NEIL J. SANDLER
By: /s/ Neil J. Sandler
--------------------------------
Name: Neil J. Sandler
Title: Managing Member
HARRI V. TARANTO
By: /s/ Harri V. Tarranto
--------------------------------
Name: Harri V. Taranto
Title: Managing Member
CUSIP No. 528872104 Page 16 of 20
Schedule 13G
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EXHIBIT INDEX
Exhibit 1. Joint Filing Agreement as required by Rule 13d-1(k)(1) under
the Securities Exchange Act of 1934, as amended.
CUSIP No. 528872104 Page 17 of 20
Schedule 13G
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EXHIBIT 1
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JOINT FILING AGREEMENT PURSUANT TO RULE 13d-1(k)(1)
Dated as of June 25, 2007
The undersigned acknowledge and agree that the foregoing statement
on Schedule 13G is filed on behalf of each of the undersigned and that all
subsequent amendments to this statement on Schedule 13G shall be filed on
behalf of each of the undersigned without the necessity of filing additional
joint filing statements. The undersigned acknowledge that each shall be
responsible for the timely filing of such amendments, and for the completeness
and accuracy of the information concerning him, her or it contained herein,
but shall not be responsible for the completeness and accuracy of the
information concerning the other entities or persons, except to the extent
that he, she or it knows or has reason to believe that such information is
inaccurate.
CUSIP No. 528872104 Page 18 of 20
Schedule 13G
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IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be
executed by their respective officers thereunto duly authorized, as of the
date first above written.
SYMPHONY CAPITAL PARTNERS, L.P.
By: Symphony Capital GP, L.P.
its general partner
By: Symphony GP, LLC
its general partner
By: /s/ Mark Kessel
--------------------------------
Name: Mark Kessel
Title: Managing Member
SYMPHONY STRATEGIC PARTNERS, LLC
By: /s/ Mark Kessel
--------------------------------
Name: Mark Kessel
Title: Managing Member
CUSIP No. 528872104 Page 19 of 20
Schedule 13G
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SYMPHONY CAPITAL GP, L.P.
By: Symphony GP, LLC
its general partner
By: /s/ Mark Kessel
--------------------------------
Name: Mark Kessel
Title: Managing Member
SYMPHONY GP, LLC
By: /s/ Mark Kessel
--------------------------------
Name: Mark Kessel
Title: Managing Member
CUSIP No. 528872104 Page 20 of 20
Schedule 13G
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MARK KESSEL
By: /s/ Mark Kessel
--------------------------------
Name: Mark Kessel
Title: Managing Member
NEIL J. SANDLER
By: /s/ Neil J. Sandler
--------------------------------
Name: Neil J. Sandler
Title: Managing Member
HARRI V. TARANTO
By: /s/ Harri V. Tarranto
--------------------------------
Name: Harri V. Taranto
Title: Managing Member