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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


                                  SCHEDULE 13G

                   UNDER THE SECURITIES EXCHANGE ACT OF 1934`

                                 (RULE 13d-102)

                 INFORMATION TO BE INCLUDED IN STATEMENTS FILED
          PURSUANT TO RULE 13D-1(b), (c) AND (d) AND AMENDMENTS THERETO
                         FILED PURSUANT TO RULE 13d-2(b)
                               (AMENDMENT NO. 1)*


                            La Jolla Pharmaceuticals
--------------------------------------------------------------------------------
                                (Name of Issuer)


                          Common Stock, $0.01 par value
--------------------------------------------------------------------------------
                         (Title of Class of Securities)


                                    503459109
--------------------------------------------------------------------------------
                                 (CUSIP Number)


                                 January 1, 2003
--------------------------------------------------------------------------------
             (Date of Event Which Requires Filing of this Statement)


Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

     / /  Rule 13d-1(b)

     /X/  Rule 13d-1(c)

     / /  Rule 13d-1(d)

     * The  remainder  of this cover  page  shall be filled out for a  reporting
person's  initial  filing on this  form with  respect  to the  subject  class of
securities,  and for any subsequent amendment containing information which would
alter the disclosures provided in a prior cover page.

     The  information  required in the remainder of this cover page shall not be
deemed to be "filed"  for the purpose of Section 18 of the  Securities  Exchange
Act of 1934 ("Act") or otherwise  subject to the  liabilities of that section of
the Act but shall be subject to all other  provisions of the Act  (however,  see
the Notes).


POTENTIAL PERSONS WHO ARE TO RESPOND TO THE COLLECTION OF INFORMATION  CONTAINED
IN THIS FORM ARE NOT  REQUIRED TO RESPOND  UNLESS THE FORM  DISPLAYS A CURRENTLY
VALID OMB CONTROL NUMBER.


SEC 1745 (3-98)



                                  SCHEDULE 13G

ISSUER: La Jolla Pharmaceuticals                            CUSIP NO.: 503459109

--------------------------------------------------------------------------------

    1. Names of Reporting Persons.
       I.R.S. Identification Nos. of above persons (entities only).

       J.P. Morgan  Partners  (BHCA),  L.P.  (formerly known as Chase Equity
       Associates, L.P.)
       13-3371826
       .........................................................................
--------------------------------------------------------------------------------

    2. Check the Appropriate Box if a Member of a Group (See Instructions)

       (a) .....................................................................

       (b) .....................................................................
--------------------------------------------------------------------------------

    3. SEC Use Only ............................................................
--------------------------------------------------------------------------------

    4.     Citizenship or Place of Organization   Delaware
                                                  ..............................
--------------------------------------------------------------------------------

                           5.  Sole Voting Power     2,055,000
                                                     ...........................
                        --------------------------------------------------------

  Number of Shares         6.  Shared Voting Power .............................
  Beneficially Owned    --------------------------------------------------------
  by Each Reporting
  Person With:             7.  Sole Dispositive Power   2,055,000
                                                        ........................
                        --------------------------------------------------------

                           8.  Shared Dispositive Power ........................
--------------------------------------------------------------------------------

    9.     Aggregate Amount Beneficially Owned by Each
           Reporting Person                               2,055,000
                                                          ......................
--------------------------------------------------------------------------------

   10.     Check if the Aggregate Amount in Row (9)
           Excludes Certain Shares (See Instructions) ..........................
--------------------------------------------------------------------------------
   11.     Percent of Class Represented by Amount in Row (9)    4.8%
                                                                ................
--------------------------------------------------------------------------------

   12.     Type of Reporting Person (See Instructions)
--------------------------------------------------------------------------------

   PN
.................................................................................

.................................................................................

.................................................................................

.................................................................................

.................................................................................

.................................................................................

--------------------------------------------------------------------------------


SEC 1745 (3-98)



                                  SCHEDULE 13G

ISSUER: La Jolla Pharmaceuticals                            CUSIP NO.: 503459109

PRELIMINARY  NOTE: This Schedule 13G has been amended to reflect a change in the
controlling  persons of the Reporting  Person as well as a decrease in ownership
percentage  as a result of an increase in  outstanding  shares which as a result
thereof  the  Reporting  Person  owns  less  than  5%  of  the  Issuer's  voting
securities.

ITEM 1.

           (A)      NAME OF ISSUER:

                    La Jolla Pharmaceuticals

           (B)      ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:

                    6455 Nancy Ridge Drive
                    San Diego, California 92121

ITEM 2.

           (A)      NAME OF PERSON FILING:

                    J.P. Morgan Partners (BHCA), L.P.

                    Supplemental  information  relating  to  the  ownership  and
                    control of the person  filing this  statement is included in
                    Exhibit 2(a) attached hereto.

           (B)      ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE, RESIDENCE:

                    1221 Avenue of the Americas
                    New York, New York  10020

           (C)      CITIZENSHIP:

                    Delaware

           (D)      TITLE OF CLASS OF SECURITIES (OF ISSUER):

                    Common Stock, par value $0.01 per share

           (E)      CUSIP NUMBER:

                    503459109

ITEM 3.  IF THIS STATEMENT IS FILED PURSUANT TOSS.SS. 240. 13D-1(B) OR 240.
         13D-2(B) OR (C), CHECK WHETHER THE PERSON FILING IS A:

           Not applicable.

ITEM 4.  OWNERSHIP

           (A)      AMOUNT BENEFICIALLY OWNED:

                    2,055,000

           (B)      PERCENT OF CLASS:

                    4.8% (as of December 31, 2002).

           (C)      NUMBER OF SHARES AS TO WHICH SUCH PERSON HAS:


SEC 1745 (3-98)




                                  SCHEDULE 13G

ISSUER: La Jolla Pharmaceuticals                            CUSIP NO.: 503459109

                (i)     Sole  power to vote or to  direct  the  vote:  2,055,000
                        shares of Common Stock.

                (ii)    Shared  power  to  vote  or  to  direct  the  vote:  Not
                        applicable.

                (iii)   Sole power to dispose or to direct the  disposition  of:
                        2,055,000 shares of Common Stock

                (iv)    Shared power to dispose or to direct the disposition of:
                        Not applicable.

ITEM 5.  OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS

             If this  statement is being filed to report the fact that as of the
date hereof the reporting  person has ceased to be the beneficial  owner of more
than five percent of the class of securities, check the following .

ITEM 6.  OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON

             Not applicable.

ITEM 7.  IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE
         SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY

             Not applicable.

ITEM 8.  IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP

             Not applicable.

ITEM 9.  NOTICE OF DISSOLUTION OF GROUP

             Not applicable.

ITEM 10. CERTIFICATION

             (a) Not applicable.

             (b) By signing  below I certify  that,  to the best of my knowledge
and belief, the securities  referred to above were not acquired and are not held
for the purpose of or with the effect of changing or influencing  the control of
the  issuer  of the  securities  and  were  not  acquired  and are  not  held in
connection  with or as a participant in any  transaction  having that purpose or
effect.


SEC 1745 (3-98)




                                  SCHEDULE 13G

ISSUER: La Jolla Pharmaceuticals                            CUSIP NO.: 503459109


                                    SIGNATURE

                  After  reasonable  inquiry and to the best of my knowledge and
belief,  I certify  that the  information  set forth in this  statement is true,
complete and correct.

Date:  February 13, 2003

                                          J.P. MORGAN PARTNERS (BHCA), L.P.


                                          By:  JPMP Master Fund Manager, L.P.,
                                               its General Partner

                                          By:  JPMP Capital Corp.,
                                               its General Partner

                                          By: /S/ JEFFREY C. WALKER
                                              ----------------------------------
                                              Name:    Jeffrey C. Walker
                                              Title:   President














SEC 1745 (3-98)