SCHEDULE 14A
                                 (Rule 14a-101)

                     Information Required in Proxy Statement

                            SCHEDULE 14A INFORMATION

                Proxy Statement Pursuant to Section 14(a) of the
                         Securities Exchange Act of 1934


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                          Bentley Pharmaceuticals, Inc.
               --------------------------------------------------
                (Name of Registrant as Specified in Its Charter)


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                          BENTLEY PHARMACEUTICALS, INC.
                                65 LAFAYETTE ROAD
                                   THIRD FLOOR
                             NORTH HAMPTON, NH 03862

                                  ------------

                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS

                                  May 22, 2002

                                  ------------

                                                             North Hampton, NH
                                                                April 18, 2002
To the Stockholders of
Bentley Pharmaceuticals, Inc.


     NOTICE IS HEREBY  GIVEN that the 2002 Annual  Meeting  (the  "Meeting")  of
Stockholders  of BENTLEY  PHARMACEUTICALS,  INC.,  a Delaware  corporation  (the
"Company"),  will be held on Wednesday,  May 22, 2002 at 11:00 a.m., local time,
at the Grand  Hyatt New York,  located at Park Avenue at Grand  Central  Station
(42nd  Street),  New York,  New York 10017 for the  purpose of  considering  and
acting upon the following matters:

     (1)  The  election  of three  Class III  Directors  to serve until the 2005
          Annual   Meeting  of   Stockholders,   or  until  the   election   and
          qualification of their respective successors; and

     (2)  The  transaction  of such other  business  as may  properly be brought
          before the meeting or any adjournment or postponement thereof.

     The Board of Directors has fixed the close of business on April 18, 2002 as
the record date for the determination of stockholders entitled to notice of, and
to vote at, the Meeting.  A complete list of the  Stockholders  entitled to vote
will be available  for  inspection  by any  Stockholder  during the Meeting;  in
addition,  the list will be open for  examination  by any  Stockholder,  for any
purpose germane to the Meeting,  during ordinary business hours, for a period of
at least 10 days  prior to the  Meeting,  at the  Company's  principal  place of
business located at 65 Lafayette Road, Third Floor, North Hampton, New Hampshire
03862.

     You are cordially invited to attend the Meeting.  Whether or not you intend
to attend the  Meeting,  you are urged to  complete,  sign and date the enclosed
form of proxy, and return it promptly in the enclosed reply envelope. No postage
is  required  if mailed in the  United  States.  Returning  your  proxy does not
deprive  you of your  right to attend  the  Meeting  and to vote your  shares in
person.  This  solicitation  is being made on behalf of the  Company's  Board of
Directors.

                                             By Order of the Board of Directors

                                             MICHAEL D. PRICE
                                             Secretary





                          BENTLEY PHARMACEUTICALS, INC.
                                65 Lafayette Road
                                   Third Floor
                             North Hampton, NH 03862

                           --------------------------

                                 PROXY STATEMENT

                       For Annual Meeting of Stockholders

                                  May 22, 2002

                            ------------------------

     This Proxy  Statement,  to be mailed to  stockholders on or about April 22,
2002, is furnished in connection with the solicitation by the Board of Directors
of Bentley  Pharmaceuticals,  Inc., a Delaware  corporation (the "Company"),  of
proxies in the  accompanying  form  ("Proxy" or  "Proxies")  for use at the 2002
Annual  Meeting of  Stockholders  of the Company to be held on Wednesday May 22,
2002 at 11:00  a.m.,  local  time at the Grand  Hyatt New York  located  at Park
Avenue at Grand Central  Station (42nd Street),  New York, New York 10017 and at
any adjournments or postponements thereof (the "Meeting").

     All Proxies  received will be voted in accordance  with the  specifications
made thereon or, in the absence of any specification, for the election of all of
the nominees  named herein to serve as  Directors.  Any Proxy given  pursuant to
this  solicitation  may be revoked by the person giving it any time prior to the
exercise  of the  powers  conferred  thereby  by notice in writing to Michael D.
Price,  Secretary of the Company, 65 Lafayette Road, Third Floor, North Hampton,
New  Hampshire  03862,  by execution  and  delivery of a subsequent  Proxy or by
attendance  and  voting  in person at the  Meeting,  except as to any  matter or
matters  upon  which,  prior to such  revocation,  a vote  shall  have been cast
pursuant to the authority conferred by such Proxy.

     Only  holders  of record of the  Company's  issued and  outstanding  Common
Stock, $.02 par value (the "Common Stock"), as of the close of business on April
18, 2002 (the "Record  Date") will be entitled to notice of, and to vote at, the
Meeting.  As of the Record Date,  there were issued and  outstanding  17,219,170
shares of the Company's Common Stock, each of which is entitled to one vote upon
each matter at the Meeting.  The holders of a majority of the shares entitled to
vote at the Meeting will  constitute a quorum for the  transaction  of business.
Proxies  submitted which contain  abstentions or broker non-votes will be deemed
present at the Meeting in determining  the presence of a quorum.  A plurality of
the votes cast at the Meeting at which a quorum is present  will be required for
the election of Directors.  Shares of Common Stock that are voted to abstain and
shares which are subject to broker  non-votes  will not be considered  cast with
respect to the proposal to elect Directors.





         SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

     The following  table sets forth  information as of April 18, 2002 as to (i)
each person  (including any "group" as that term is used in Section  13(d)(3) of
the Securities  Exchange Act of 1934, as amended) who is known to the Company to
be the beneficial owner of more than five percent of the Company's Common Stock,
its only class of voting securities, (ii) each Director and nominee for Director
of the Company,  (ii) each Executive Officer of the Company named in the Summary
Compensation Table set forth below, and (iii) all current executive officers and
directors as a group.

     Unless otherwise indicated,  the Company believes that all persons named in
the table have sole voting and  investment  power with respect to all securities
beneficially owned by them. Beneficial ownership exists when a person either has
the power to vote or sell common stock.  A person is deemed to be the beneficial
owner of securities  that can be acquired by such person within 60 days from the
applicable  date,  whether upon the exercise of options or otherwise.  Except as
otherwise indicated,  the address for those beneficial holders who own more than
5% of the Company's Common Stock is the address for the Company's headquarters.




                                                                                                PERCENTAGE
                                                                     NUMBER OF SHARES OF         OF COMMON
                                                                         COMMON STOCK              STOCK
NAME AND ADDRESS OF BENEFICIAL OWNER                                  BENEFICIALLY OWNED        OUTSTANDING
------------------------------------                                  ------------------        -----------
                                                                                            
Michael McGovern(1)..........................................             2,793,428               14.96%
  Director
  5910 Long Island Drive
  Atlanta, GA 30328
Renaissance   U.S.  Growth  and  Income  Trust PLC(2)........             1,104,400                6.41%
  8080 North Central Expressway
  Suite 210, LB59
  Dallas, TX  75206-1857
Renaissance  Capital  Growth and  Income  Fund III, Inc.(3)..               924,979                5.37%
  8080 North Central Expressway
  Suite 210, LB59
  Dallas, TX  75206-1857
Salomon Smith Barney Holdings Inc.(4)........................               747,333                4.34%
  388 Greenwich Street
  New York, NY 10013
Citigroup Inc.(4)
  399 Park Avenue
  New York, NY 10043
James R. Murphy(5)...........................................               911,694                5.06%
  Chairman of the Board, President, Chief
  Executive Officer and Director
Robert M. Stote, M.D.(6).....................................               630,345                3.54%
  Senior Vice President, Chief Science
  Officer and Director
Michael D. Price(7)..........................................               530,001                2.99%
  Vice President, Chief Financial Officer,
  Secretary, Treasurer and Director
Robert J. Gyurik(8)..........................................               144,544                  *
  Vice President of Pharmaceutical
  Development and Director
Jordan A. Horvath(9).........................................                57,184                  *
  Vice President and General Counsel
                                                                         (table continues on next page)

                                       2



                                                                                                PERCENTAGE
                                                                     NUMBER OF SHARES OF         OF COMMON
                                                                         COMMON STOCK              STOCK
NAME AND ADDRESS OF BENEFICIAL OWNER (continued)                      BENEFICIALLY OWNED        OUTSTANDING
------------------------------------                                  ------------------        -----------
                                                                                              
Charles L. Bolling(10).......................................               103,528                  *
  Director
Miguel Fernandez(11).........................................                77,568                  *
  Director
William A. Packer(12)........................................                72,800                  *
  Director
All executive officers and directors as a group
(9 persons)(13)..............................................             5,321,092               25.41%
---------------------------------
*       Less than one percent


(1)  Includes  1,313,500  shares of the  Company's  Common Stock  issuable  upon
     exercise of Class B Warrants,  75,000 shares of the Company's  Common Stock
     issuable  upon  exercise of vested stock  options and 69,200  shares of the
     Company's  Common Stock issuable upon exercise of stock options that become
     exercisable within 60 days. Excludes 100,000 shares of the Company's Common
     Stock issuable upon exercise of stock options which are not vested.

(2)  The number of shares is based on  information  contained in Amendment No. 5
     to Schedule 13G,  dated  December 26, 2000.  The Schedule 13G was signed by
     Russell  Cleveland as President of  Renaissance  Capital  Group,  Inc., the
     investment  manager of  Renaissance  U.S.  Growth and Income Trust PLC. Mr.
     Cleveland is a former Director of the Company.

(3)  The number of shares is based on  information  contained in Amendment No. 7
     to Schedule  13G,  dated  December 7, 2000.  The Schedule 13G was signed by
     Russell  Cleveland as President and CEO of  Renaissance  Capital Growth and
     Income Fund III, Inc. Mr. Cleveland is a former Director of the Company.

(4)  The number of shares is based on  information  contained  in Schedule  13G,
     dated  February 6, 2002.  Salomon Smith Barney  Holdings Inc. and Citigroup
     Inc.  filed the  Schedule  13G as a group,  indicating  shared  voting  and
     dispositive power of the securities held.

(5)  Includes 1,300 shares of the Company's  Common Stock owned by Mr.  Murphy's
     sons,  as to which Mr. Murphy  disclaims  beneficial  ownership,  and 3,907
     shares of the Company's Common Stock held in Mr. Murphy's 401(k) Retirement
     Plan. Also includes  745,400 shares of the Company's  Common Stock issuable
     upon  exercise of vested  stock  options,  57,600  shares of the  Company's
     Common  Stock   issuable   upon  exercise  of  stock  options  that  become
     exercisable  within 60 days and 1,500 shares of the Company's  Common Stock
     issuable upon exercise of Class B Warrants.  Excludes 100,000 shares of the
     Company's  Common Stock  issuable  upon exercise of stock options which are
     not vested.

(6)  Includes  4,145 shares of the  Company's  Common Stock held in Dr.  Stote's
     401(k)  Retirement  Plan,  567,500  shares of the  Company's  Common  Stock
     issuable  upon  exercise  of vested  stock  options,  10,000  shares of the
     Company's  Common Stock issuable upon exercise of stock options that become
     exercisable  within 60 days and 5,000 shares of the Company's  Common Stock
     issuable upon exercise of Class B Warrants.  Excludes  37,500 shares of the
     Company's  Common Stock  issuable  upon exercise of stock options which are
     not vested.

(7)  Includes 101 shares of the Company's Common Stock owned by Mr. Price's son,
     as to which Mr. Price disclaims beneficial  ownership,  and 4,198 shares of
     the Company's Common Stock held in Mr. Price's 401(k) Retirement Plan. Also
     includes  446,500  shares  of the  Company's  Common  Stock  issuable  upon
     exercise of vested stock options and 50,000 shares of the Company's  Common
     Stock issuable upon exercise of stock options that become

                                               (footnotes continue on next page)

                                       3


    exercisable within 60 days. Excludes 50,000 shares of the Company's Common
    Stock issuable upon exercise of stock options which are not vested.

(8)  Includes 9,970 shares of the Company's Common Stock and 1,000 shares of the
     Company's  Common Stock issuable upon exercise of Class B Warrants owned by
     Mr. Gyurik's IRA and 3,574 shares of the Company's Common Stock held in Mr.
     Gyurik's  401(k)  Retirement  Plan.  Also  includes  40,000  shares  of the
     Company's  Common Stock  issuable upon exercise of vested stock options and
     50,000 shares of the Company's Common Stock issuable upon exercise of stock
     options that become exercisable within 60 days.  Excludes 100,000 shares of
     the  Company's  Common Stock  issuable upon exercise of stock options which
     are not vested.

(9)  Includes 50,000 shares of the Company's Common Stock issuable upon exercise
     of vested stock options and 2,884 shares of the Company's Common Stock held
     in Mr.  Horvath's 401(k)  Retirement  Plan.  Excludes 120,000 shares of the
     Company's  Common Stock  issuable  upon exercise of stock options which are
     not vested.

(10) Includes 67,628 shares of the Company's Common Stock issuable upon exercise
     of vested stock  options and 27,900  shares of the  Company's  Common Stock
     issuable upon exercise of stock options that become  exercisable  within 60
     days.

(11) Includes 44,200 shares of the Company's Common Stock issuable upon exercise
     of vested stock  options and 27,900  shares of the  Company's  Common Stock
     issuable upon exercise of stock options that become  exercisable  within 60
     days.

(12) Includes 44,200 shares of the Company's Common Stock issuable upon exercise
     of vested stock  options and 27,900  shares of the  Company's  Common Stock
     issuable upon exercise of stock options that become  exercisable  within 60
     days.

(13) Includes 1,401 shares of the Company's Common Stock owned by family members
     of  certain  of the  executive  officers  and  directors,  as to which each
     executive officer or director disclaims beneficial ownership. Also includes
     2,080,428  shares of the Company's  Common Stock  issuable upon exercise of
     vested stock  options,  320,500  shares of the Company's  Common Stock that
     become exercisable within 60 days, 1,320,000 shares of the Company's Common
     Stock  issuable  upon  exercise of Class B Warrants,  18,708  shares of the
     Company's  Common Stock held in 401(k)  Retirement Plan accounts of various
     executive officers and 9,970 shares of the Company's Common Stock and 1,000
     shares of the  Company's  Common Stock  issuable  upon  exercise of Class B
     Warrants held by the IRA account of an executive officer.  Excludes 507,500
     shares of the  Company's  Common  Stock  issuable  upon  exercise  of stock
     options which are not vested.



                                       4



                                   PROPOSAL 1

                              ELECTION OF DIRECTORS

     The  Company's   Articles  of  Incorporation  and  By-Laws  provide  for  a
classified  Board  of  Directors.  The  Board  is  divided  into  three  classes
designated  Class I, Class II and Class III. The nominees  included in Class III
below are being  presented  for  election as Class III  Directors to hold office
until  the  2005  Annual  Meeting  of  Stockholders.  Unless  instructed  to the
contrary,  the  persons  named in the  enclosed  Proxy  intend to cast all votes
pursuant to Proxies  received in favor of the persons  listed  under the heading
"Nominees" below as Directors.  The nominees have indicated to the Company their
availability  for election;  Messrs.  Murphy,  Stote and Fernandez are presently
Directors.  In the event that the  nominees  should not continue to be available
for election,  the holders of the Proxies may exercise their  discretion to vote
for a  substitute.  Officers  hold  office  until  the  meeting  of the Board of
Directors  following  each  Annual  Meeting  of  Stockholders  and  until  their
successors have been chosen and qualified.

     The  following  information  is furnished  with respect to the nominees and
each other continuing member of the Company's Board of Directors.



                                                                              CLASS OF     YEAR
                                   POSITIONS WITH                             DIRECTOR     FIRST
                                   THE COMPANY                                (UPON        BECAME
NAME                      AGE      PRESENTLY HELD                             ELECTION)    DIRECTOR
----                      ---      --------------                             ---------    --------

NOMINEES:

                                                                                
James R. Murphy           52       Chairman of the Board, President,            III         1993
                                   Chief Executive Officer and Director

Robert M. Stote, M.D.     62       Senior Vice President, Chief                 III         1993
                                   Science Officer and Director

Miguel Fernandez          71       Director                                     III         1999



DIRECTORS WHOSE TERMS OF OFFICE
CONTINUE AFTER THE MEETING:

Michael McGovern          58       Vice Chairman and Director                    I          1997

Michael D. Price          44       Vice President, Chief Financial               I          1995
                                   Officer, Secretary, Treasurer
                                   and Director

Charles L. Bolling        78       Director                                      II         1991

Robert J. Gyurik          55       Vice President of Pharmaceutical              II         1998
                                   Development and Director

William A. Packer         67       Director                                      II         1999




                                       5



BACKGROUND OF NOMINEES

     JAMES R. MURPHY has served as one of the  Company's  Directors  since 1993.
Mr. Murphy became  President of the Company in September  1994,  was named Chief
Executive  Officer  effective  January 1995 and became  Chairman of the Board in
June 1995.  Prior to rejoining the Company,  Mr. Murphy served as Vice President
of  Business   Development   at   MacroChem   Corporation,   a  publicly   owned
pharmaceutical  and drug  delivery  company,  from March 1993 through  September
1994. From September 1992 until March 1993, Mr. Murphy served as a consultant in
the  pharmaceutical  industry with his primary  efforts  directed toward product
licensing.  Prior  thereto,  Mr. Murphy served as Director - Worldwide  Business
Development  and  Strategic  Planning  of the  Company  from  December  1991  to
September 1992. Mr. Murphy previously spent 14 years in pharmaceutical  research
and  product  development  with  SmithKline  Corporation  and  in  international
business  development with contract  research and consulting  laboratories.  Mr.
Murphy received a B.A. in Biology from Millersville University.

     ROBERT M. STOTE,  M.D.  became  Senior  Vice  President  and Chief  Science
Officer of the  Company  in March  1992 and has  served as one of the  Company's
Directors since 1993.  Prior to joining the Company,  Dr. Stote was employed for
20 years by  SmithKline  Beecham  Corporation  serving in a variety of executive
clinical research  positions.  Dr. Stote was Chief of Nephrology at Presbyterian
Medical Center of Philadelphia  from 1972 to 1989 and was Clinical  Professor of
Medicine at the University of Pennsylvania.  Dr. Stote also serves as a Director
of Datatrak International, Inc. and of Auxilium Pharmaceuticals,  Inc. Dr. Stote
received a B.S. in Pharmacy  from the Albany  College of Pharmacy,  an M.D. from
Albany  Medical  College  and  is  Board  Certified  in  Internal  Medicine  and
Nephrology.  He was a Fellow in  Nephrology  and  Internal  Medicine at the Mayo
Clinic and is currently a Fellow of the American College of Physicians.

     MIGUEL  FERNANDEZ has served as one of the Company's  Directors since 1999.
Mr.  Fernandez  served  from  1980  to 1996 as  President  of the  International
Division and corporate  Vice  President at  Carter-Wallace,  Inc.,  where he was
responsible  for all product lines outside of the United States.  Prior thereto,
Mr. Fernandez was employed for approximately  eight years by SmithKline Beecham,
where his last position was Vice President for Latin America.  Before SmithKline
Beecham,  Mr.  Fernandez  served  as  Managing  Director  of Warner  Lambert  in
Argentina  for two years.  From 1962 to 1970,  Mr.  Fernandez  was  employed  by
Merck/Frost in Canada. Mr. Fernandez attended the University of British Columbia
in Canada  and  received  an M.B.A.  from the Ivey  School  of  Business  at the
University of Western Ontario in London, Ontario, Canada. Mr. Fernandez has been
retired since 1996.


BACKGROUND OF CONTINUING DIRECTORS

     MICHAEL  MCGOVERN has served as one of the Company's  Directors  since 1997
and was named Vice Chairman of the Company in October 1999. Mr.  McGovern serves
as President of McGovern  Enterprises,  a provider of  corporate  and  financial
consulting  services,  which he founded in 1975. Mr. McGovern is Chairman of the
Board of Specialty Surgicenters,  Inc. and Training Solutions Interactive, Inc.;
is Vice Chairman of the Board of Employment Technologies, Inc. and is a Director
on the  corporate  board  of the  Reynolds  Development  Company.  Mr.  McGovern
received a B.S. and M.S. in accounting  and his Juris Doctor from the University
of Illinois.

     MICHAEL D. PRICE became Chief Financial Officer,  Vice  President/Treasurer
and  Secretary of the Company in October  1993,  April 1993 and  November  1992,
respectively,  and has served as one of the Company's  Directors  since 1995. He
has served the Company in other  capacities  since March 1992.  Prior to joining
the Company, he was employed as a financial and management  consultant with Carr
Financial Group from March 1990 to March 1992. Prior thereto, he was employed as
Vice President of Finance with Premiere  Group,  Inc. from June 1988 to February
1990.  Prior thereto,  Mr. Price was employed by Price  Waterhouse  from January
1982 to June  1988  where  his  last  position  with  that  firm was as an Audit
Manager.   Mr.  Price  received  a  B.S.  in  Business   Administration  with  a
concentration  in Accounting from Auburn  University and an M.B.A.  from Florida
State  University.  Mr. Price is a Certified Public  Accountant  licensed by the
State of Florida.


                                       6


     CHARLES L. BOLLING has served as one of the Company's Directors since 1991.
Mr. Bolling served from 1968 to 1973 as Vice President of Product Management and
Promotion (U.S.), from 1973 to 1977 as Vice President of Commercial  Development
and from 1977 to 1986 as  Director of Business  Development  (International)  at
SmithKline & French Laboratories. Mr. Bolling has been retired since 1986.

     ROBERT J. GYURIK has served as one of the  Company's  Directors  since 1998
and became Vice President of Pharmaceutical  Development of the Company in March
1999.  Mr. Gyurik was Manager of  Development  and Quality  Control at MacroChem
Corporation,  a position  he held from May 1993 to February  1999.  From 1971 to
1993 Mr.  Gyurik  worked  in  various  research  and  development  positions  at
SmithKline Beecham.  Prior thereto, Mr. Gyurik worked at Schering as a Medicinal
Chemist.  Mr. Gyurik  received a B.A. in Biology and Chemistry  from  Immaculata
College. Mr. Gyurik is a member of the American Chemical Society,  International
Society for Chronobiology and the New York Academy of Sciences.

     WILLIAM A. PACKER has served as one of the Company's  Directors since 1999.
Mr.  Packer  has  been  a  business  and  industry  consultant  to a  number  of
biopharmaceutical  companies  since 1998.  From 1992 until 1998,  Mr. Packer was
President  and Chief  Financial  Officer of Virus  Research  Institute,  Inc., a
publicly owned biotechnology  company. Prior to this, Mr. Packer was employed by
SmithKline Beecham Plc, where he held various senior management  positions,  the
most  recent as Senior Vice  President,  Biologicals,  in which  position he was
responsible  for the direction of  SmithKline's  global  vaccine  business.  Mr.
Packer is a Chartered Accountant.


COMMITTEES OF THE BOARD OF DIRECTORS; BOARD OF DIRECTORS MEETINGS

     The Board of Directors has an Audit Committee, a Compensation Committee and
a Strategic Planning Committee.  The Audit Committee  recommends to the Board of
Directors  the  appointment  of  independent  auditors  to audit  the  Company's
consolidated  financial  statements,  reviews  the  Company's  internal  control
procedures  and advises the Company on tax and other matters  connected with the
finances and reporting  obligations  of the Company.  The Audit  Committee  also
reviews  with  management  the  annual  audit and other  work  performed  by the
independent auditors. The Compensation Committee administers the Company's Stock
Option Plans and reviews and recommends to the Board of Directors the nature and
amount  of  compensation  to be paid to the  Company's  executive  officers  and
employees  that earn in excess of  $100,000  annually.  The  Strategic  Planning
Committee  advises  the Board  and  Management  with  respect  to the  strategic
direction  of the Company.  The Audit  Committee  currently  consists of Messrs.
Charles   Bolling,   Miguel  Fernandez  and  William  Packer   (chairman);   the
Compensation  Committee  currently consists of Messrs.  Charles Bolling,  Miguel
Fernandez,  Michael  McGovern  (chairman) and William Packer;  and the Strategic
Planning  Committee  currently  consists  of  Messrs.  Charles  Bolling,  Miguel
Fernandez (chairman), Michael McGovern, James Murphy and William Packer.

     During  2001,  the  Board of  Directors  held  eight  meetings,  the  Audit
Committee held 2 meetings,  the  Compensation  Committee held 6 meetings and the
Strategic  Planning  Committee held 3 meetings.  Each Director attended at least
75% of the total  number of meetings of the Board of  Directors  which were held
during the period he served as a Director in 2001 and meetings of each Committee
on which such Director served.

                                       7


COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION

     The members of the Compensation  Committee during 2001 were Messrs. Charles
L. Bolling,  Russell Cleveland,  Miguel Fernandez,  Michael McGovern and William
Packer,  all of whom  were at the time of  service  non-employee  Directors.  No
member of the Compensation Committee has a relationship that would constitute an
interlocking relationship with Executive Officers or Directors of the Company or
another entity.

REMUNERATION OF NON-EMPLOYEE DIRECTORS

     The Company pays  Directors who are not  employees  fees of $3,000 for each
in-person meeting of the Board of Directors, $500 for each telephone meeting and
$500 for each committee  meeting  attended,  which do not take place on the same
day as board meetings, in addition to reimbursing expenses incurred in attending
meetings.  Each Director who is not an employee is automatically granted options
to purchase a number of shares of the Company's Common Stock equal to 2/10 of 1%
of the number of  outstanding  shares of the Company's  Common Stock upon his or
her election to the board. Thereafter,  each continuing non-employee Director is
entitled to receive  annually,  options to purchase  the number of shares of the
Company's  Common Stock equal to 2/10 of 1% of the number of outstanding  shares
of  the  Company's   Common  Stock   outstanding  on  the  date  of  our  annual
stockholder's  meeting.  For his additional time and effort,  Mr. McGovern,  the
Company's  Vice Chairman,  was awarded  additional  options to purchase  100,000
shares of Common  Stock for each of 2000 and 2001 and  50,000  for 2002.  During
2001,  options  to  purchase  239,500  shares of Common  Stock  were  granted to
Directors who are not employees at exercise  prices  ranging from $5.70 to $7.10
per share,  representing not less than the fair market value of the Common Stock
on the dates of the grants.  These options  expire on dates ranging from January
1, 2011 to August 30, 2011.


                                       8

                             EXECUTIVE COMPENSATION

SUMMARY COMPENSATION TABLE

     The following  table sets forth the total  compensation  for 1999, 2000 and
2001 paid to or accrued by the Company for the Chief  Executive  Officer and the
executive  officers at December 31, 2001 whose total cash  compensation  in 2001
exceeded $100,000.  Except as provided in the table below or otherwise discussed
below, the Company paid no other compensation to them.

                           SUMMARY COMPENSATION TABLE



                                                                                        Long-Term Compensation
                                                                                  ----------------------------------
                                                      Annual Compensation                Awards              Payouts
                                                      -------------------         ------------------------   -------
                                                                                               Securities
                                                                        Other    Restricted    Underlying      LTIP       All
                                                                        Annual     Stock        Options/     Payouts     Other
Name and Principal Position          Year   Salary ($)   Bonus ($)   Comp.($)(1)  Awards($)      SARs (#)      ($)       Comp.
---------------------------          ----   ----------   ---------   -----------  ---------      --------    -------     -----
                                                                                                 
James R. Murphy (2)............      2001     $390,000    $100,000     $12,000        ---           ---          ---     $70,135
  Chairman of the Board,             2000     $366,923    $170,000     $12,000        ---           ---          ---     $11,984
  President, Chief Executive         1999     $295,577      ---          ---      $120,000          ---          ---      $6,389
  Officer and Director

Robert M. Stote (3)............      2001     $121,752     $15,000       ---          ---           ---          ---     $12,336
  Senior Vice President, Chief       2000     $ 94,589     $15,000       ---          ---           ---          ---     $12,336
  Science Officer and Director       1999     $110,449      ---          ---      $ 22,500          ---          ---      $6,836

Michael D. Price (4)...........      2001     $212,000     $50,000       ---      $ 39,313          ---          ---     $22,114
  Vice President, Chief              2000     $188,685     $30,000       ---          ---           ---          ---     $11,007
  Financial Officer,                 1999     $176,231         ---       ---      $ 22,500          ---          ---      $5,507
  Treasurer, Secretary and
  Director

Robert J. Gyurik (5)...........      2001     $175,000     $50,000       ---         ---            ---          ---     $42,081
  Vice President of                  2000     $138,903     $30,000       ---         ---            ---          ---     $10,973
  Pharmaceutical Development         1999     $ 99,808      ---          ---      $ 67,500          ---          ---       ---
  and Director

Jordan A. Horvath (6)..........      2001     $304,500      ---          ---         ---            ---          ---     $10,757
  Vice President and General         2000     $112,734      ---          ---         ---            ---          ---     $    16
  Counsel

-------------------------------------

(1)  The value of perquisites  provided to the named executive  officers did not
     exceed $50,000 or 10% of total compensation in any case.

(2)  "All Other Compensation" for Mr. Murphy includes:

     o    in 2001,  principal and interest of $55,537 forgiven on a loan made by
          the Company to Mr.  Murphy in 2000 to assist Mr.  Murphy's  payment of
          taxes on shares of the  Company's  Common Stock awarded by the Company
          to him in  1999;
     o    matching  contributions  in cash to Mr.  Murphy's  401(k)  plan in the
          amount of $970 in 2000 and $5,000 in 1999;
     o    matching  contributions in shares of the Company's Common Stock to Mr.
          Murphy's 401(k) plan valued at $10,500 in 2001 and $9,530 in 2000; and
     o    life insurance  premiums of $4,098 in 2001,  $1,484 in 2000 and $1,389
          in 1999.

(3)  "All Other Compensation" for Dr. Stote includes:

     o    matching  contributions  in cash  to Dr.  Stote's  401(k)  plan in the
          amount of $283 in 2000 and $5,000 in 1999;
     o    matching  contributions in shares of the Company's Common Stock to Dr.
          Stote's 401(k) plan valued at $10,500 in 2001 and $10,217 in 2000; and
     o    life insurance premiums of $1,836 in 2001, 2000 and 1999.

  (4) "All Other Compensation" for Mr. Price includes:

     o    in 2001,  principal and interest of $11,107 forgiven on a loan made by
          the  Company  to Mr.  Price in 2000 to assist Mr.  Price's  payment of
          taxes on shares of the  Company's  Common Stock awarded by the Company
          to him in 1999;
     o    matching  contributions  in cash  to Mr.  Price's  401(k)  plan in the
          amount of $551 in 2000 and $5,000 in 1999;
     o    matching  contributions in shares of the Company's Common Stock to Mr.
          Price's 401(k) plan valued at $10,500 in 2001 and $9,949 in 2000; and
     o    life  insurance  premiums of $507 in 2001,  2000 and 1999.

                                               (footnotes continue on next page)

                                       9


(5)  Mr. Gyurik joined the Company in March 1999. "All Other  Compensation"  for
     Mr. Gyurik includes:

     o    in 2001,  principal and interest of $31,030 forgiven on a loan made by
          the Company to Mr.  Gyurik in 2000 to assist Mr.  Gyurik's  payment of
          taxes on shares of the  Company's  Common Stock awarded by the Company
          to him in 1999;
     o    matching  contributions  in cash to Mr.  Gyurik's  401(k)  plan in the
          amount of $263 in 2000;
     o    matching  contributions in shares of the Company's Common Stock to Mr.
          Gyurik's  401(k)  plan  valued at $10,500 in 2001 and $10,237 in 2000;
          and
     o    life insurance premiums of $551 in 2001 and $473 in 2000.

(6)  Mr. Horvath joined the Company in August 2000. "All Other Compensation" for
     Mr. Horvath includes:

     o    matching  contributions in shares of the Company's Common Stock to Mr.
          Horvath's 401(k) plan valued at $10,500 in 2001; and
     o    life insurance premiums of $257 in 2001 and $16 in 2000.

     The Company has entered  into  employment  agreements  with each of Messrs.
Murphy,  Stote,  Price,  Gyurik and Horvath which set forth their  relationships
with the Company.  The agreements expire on December 31, 2003 and renew annually
for one year terms. Under the agreements,  each individual is paid a base salary
and  provided  with life  insurance,  with salary  increases,  bonuses and stock
option grants at the discretion of the board's  compensation  committee  (except
for Mr. Murphy's  agreement,  which provides for a minimum stock option grant of
50,000 options per annum and Mr. Horvath's initial agreement, which provides for
minimum salary  increases of 5% per year). All employees are full time, with the
exception of Dr. Stote who is a part-time employee.

     The  agreements  may be  terminated on one year's notice and, if terminated
earlier without cause,  upon payment of severance equal to one year's salary,  a
bonus equal to the greater of the  employee's  bonus target for the current year
or actual bonus for the prior year and vesting of options based on the number of
months  employment  during the vesting  period.  If the  employee is  terminated
within 12  months of a change of  control  of the  Company,  or if the  employee
terminates his employment within 12 months after a change of control because his
job changes,  the Company breaches his employment agreement or he is required to
move his residence,  then the severance is increased to twice his annual salary,
twice the  average of bonuses in the prior two years,  immediate  vesting of all
stock  options  and  continuation  of  health  benefits  for two years (or until
receiving comparable benefits from another employer),  and the option to keep in
place life  insurance  at the  employee's  expense.  No  severance  is paid on a
termination for cause. In Mr. Murphy's  agreement,  severance following a change
in control is 2.99 times salary.  Mr. Horvath's initial agreement provides that,
on  termination  without  cause,   severance  will  be  two  years'  salary  and
acceleration  of all  options  and,  following a  termination  after a change of
control, severance will be 2.99 times salary and bonus.

STOCK OPTION PLANS

     1991 Stock Option Plan. The Company's 1991 Stock Option Plan was adopted in
1991 and was amended  several  times to increase  the number of shares  issuable
under it to a total of  1,000,000.  While no options  could be granted under the
1991 plan after  September 30, 2001, all options granted prior to that date will
continue to vest and remain outstanding in accordance with the terms of the 1991
Plan.

     2001 Employee's Stock Option Plan. The Company's 2001 Employee Stock Option
Plan was adopted and  approved in 2001.  The Company may issue  incentive  stock
options, as defined in the Internal Revenue Code of 1986, or non-qualified stock
options to purchase up to 1,000,000  shares of the Company's Common Stock to the
Company's  employees under this plan.  During 2001,  options to purchase 123,500
shares of the  Company's  Common  Stock were  granted to  employees  who are not
executive  officers.  Such options were granted at prices  ranging from $5.25 to
$7.90 per share,  representing  the fair market  value of the  Company's  Common
Stock on the dates of grant.  These options expire on various dates ranging from
May 9, 2011 to November 8, 2011.

                                       10


     2001  Directors'  Stock Option Plan.  The Company's 2001  Directors'  Stock
Option  Plan  was  adopted  and   approved  in  2001.   The  Company  may  issue
non-qualified  stock  options to purchase up to 500,000  shares of the Company's
Common Stock to our Directors under this plan.

     The  following  table  sets forth the  details  of  options  granted to the
individuals  listed in the Summary  Compensation  table  during  2001.  No stock
appreciation rights have been granted to date.

                      OPTION/SAR GRANTS IN LAST FISCAL YEAR



                                                                                                              POTENTIAL
                                                                                                              REALIZABLE
                                                                                                               VALUE AT
                                                      INDIVIDUAL GRANTS                                        ASSUMED
                              ---------------------------------------------------------------                ANNUAL RATES
                                NUMBER OF          % OF TOTAL                                               OF STOCK PRICE
                                SECURITIES        OPTIONS/SARS        EXERCISE                               APPRECIATION
                                UNDERLYING         GRANTED TO         OR BASE                              FOR OPTION TERMS
                                 OPTIONS          EMPLOYEES IN         PRICE       EXPIRATION              ----------------
NAME                           GRANTED (#)         FISCAL YEAR       ($/SHARE)        DATE             5% ($)           10% ($)
----                           -----------         -----------       ---------        ----             ------           -------

                                                                                                   
James R. Murphy .........         75,000              13.7%        $5.88 - $6.00   1/1 - 5/9/11        $281,635       $713,718
Robert M. Stote, M.D.....         10,000               1.8%            $6.00          5/9/11           $ 37,734       $ 95,625
Michael D. Price ........         50,000               9.1%            $6.00          5/9/11           $188,688       $478,123
Robert J. Gyurik.........         50,000               9.1%            $6.00          5/9/11           $188,688       $478,123
Jordan A. Horvath........          ---                ---               ---             ---              ---          ---




     The following  table sets forth certain  information  concerning the number
and value at December 31, 2001 of shares of the  Company's  Common Stock subject
to  unexercised   options  held  by  the  individuals   listed  in  the  Summary
Compensation  Table.  No shares of the  Company's  Common Stock were acquired by
these individuals on exercise of stock options in 2001.

              AGGREGATED OPTION EXERCISES IN LAST FISCAL YEAR AND
                         FISCAL YEAR-END OPTION VALUES



                                                    NUMBER OF SECURITIES                      VALUE OF UNEXERCISED
                                                   UNDERLYING UNEXERCISED                         IN-THE-MONEY
                                                   OPTIONS/SARS AT FY-END                         OPTIONS/SARS
                                                         (# SHARES)                              AT FY-END($)(1)
                                                         ----------                              ---------------
NAME                                           EXERCISABLE        UNEXERCISABLE            EXERCISABLE        UNEXERCISABLE
----                                           -----------        -------------            -----------        -------------

                                                                                                       
James R. Murphy.........................           745,400               57,600             $4,574,706             $241,344
Robert M. Stote, M.D....................           567,500               10,000             $3,496,316              $41,900
Michael D. Price........................           446,500               50,000             $2,778,957             $209,500
Robert J. Gyurik........................            40,000               50,000              $ 122,850             $209,500
Jordan A. Horvath.......................            50,000              100,000              $ 122,000             $244,000
--------------


(1)  Based  on the  difference  between  the  closing  price  per  share  of the
     Company's Common Stock on December 31, 2001 and the option exercise prices.

     No long-term  incentive plan awards were granted to the individuals  listed
in the Summary Compensation table during 2001.


                                       11


COMPLIANCE WITH SECTION 16(A) OF THE SECURITIES EXCHANGE ACT

     Section 16(a) of the Securities Exchange Act of 1934, as amended,  requires
the Company's  executive  officers and  directors,  and any persons who own more
than 10% of any  class  of the  Company's  equity  securities,  to file  certain
reports  relating  to their  ownership  of such  securities  and changes in such
ownership  with the  Securities  and Exchange  Commission,  the  American  Stock
Exchange and the Pacific  Stock  Exchange and to furnish the Company with copies
of such reports.  To the  Company's  knowledge,  during 2001,  all Section 16(a)
filing requirements have been satisfied.


401(K) RETIREMENT PLAN

     The Company  sponsors a 401(k)  retirement  plan (the "401(k)  Plan") under
which eligible employees may contribute,  on a pre-tax basis, between 1% and 15%
of their  respective  total annual income from the Company,  subject to maximums
set by U.S. tax law.  All  full-time  employees  who work for the Company in the
U.S. are eligible to participate in the 401(k) Plan. All employee  contributions
are allocated to the employee's  individual  account and are invested in various
investment  options as directed by the employee.  Employees' cash  contributions
are fully vested and nonforfeitable.  The Company made matching contributions to
the 401(k) Plan in 2001 by granting 13,658 shares of the Company's  Common Stock
valued  at  $82,959.  The  Company  currently  matches  100%  of  each  eligible
employee's  contribution in 2002 with shares of the Company's  Common Stock. All
of the Company's  matching  contributions  vest 25% each year for the first four
years of each employee's employment.



                 CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

     In March 2000 the Company made loans to three executive  officers to assist
each of them in making their  income tax  payments  for shares of the  Company's
Common  Stock which the  Company  granted to them in 1999.  The  Company  loaned
$250,000 to Mr.  Murphy,  $50,000 to Mr. Price and $140,000 to Mr.  Gyurik.  The
loans bear interest at the rate of 2.37% annually, are due in March 2003 and are
secured by shares of the Company's  Common Stock owned by the three  individuals
(Mr. Murphy, 18,700 shares; Mr. Price, 4,000 shares; Mr. Gyurik, 10,700 shares).
Interest on the loans accrues quarterly.  In December 2001 and January 2002, the
Company  agreed to forgive  part of the  principal  and interest on the loans as
detailed in the  following  chart.  All of the amounts  forgiven are  considered
income to the three individuals.




                                                                 JAMES R. MURPHY      MICHAEL D. PRICE       ROBERT J. GYURIK
                                                                 ---------------      ----------------       ----------------
                                                                                                            
Initial amount of loan.................................                 $250,000               $50,000               $140,000
   Principal forgiven in December 2001.................                   27,850                 5,570                 15,879
   Interest forgiven in December 2001..................                   27,687                 5,537                 15,151
   Principal forgiven in January 2002..................                   55,209                11,042                 30,847
   Interest forgiven in January 2002...................                      439                    88                    245
Principal balance at March 31, 2002....................                 $166,941               $33,388                $93,274




                                       12


AUDIT COMMITTEE REPORT

     In accordance with its charter adopted by the Board of Directors, the Audit
Committee assists the Board in fulfilling its  responsibilities  relating to the
Company's  audited  financial  reports,   accounting  procedures  and  financial
controls.  The  Audit  Committee  reviews  the  procedures  and  results  of the
Company's  independent audits, and provides a direct  communications link to the
Board of  Directors  from  Deloitte & Touche,  LLP,  the  Company's  independent
auditors,  and the Company's chief financial  officer to help assure the quality
of the Company's financial reporting and control systems.

     During 2001, the Audit  Committee met 2 times and the committee  chair,  as
representative  of the committee,  and members of the committee held discussions
with the chief financial officer and independent  auditors regarding the interim
financial  information contained in the Company's quarterly reports on Form 10-Q
prior to filing with the Securities and Exchange Commission.


     Auditor  Independence  and 2001 Audit.  To fulfill  its  duties,  the Audit
Committee  obtained  a  formal  written  report  of  the  independent   auditors
describing  all  relationships  between the  auditors and the Company that might
bear on the auditors' independence  consistent with Independence Standards Board
Standard No. 1,  "Independence  Discussions with Audit  Committee." In addition,
the Audit  Committee  discussed  with the  auditors any  relationships  that may
impact  their  objectivity  and  independence  and  satisfied  itself  as to the
auditors'  independence.  The Audit Committee also discussed with management and
the  independent  auditors  the quality and adequacy of the  Company's  internal
controls. The Audit Committee reviewed with the independent auditors their audit
plans, audit scope and identification of audit risks.

     The Audit Committee  discussed and reviewed with the  independent  auditors
all communications required by generally accepted auditing standards,  including
those  described  in  Statement  on  Auditing  Standards  No.  61,  as  amended,
"Communication with Audit Committee" and reviewed the results of the independent
auditors' examination of the financial statements.

     2001 Financial  Statements and Recommendations of the Committee.  The Audit
Committee reviewed the Company's audited financial  statements as of and for the
year ended  December  31, 2001 with  management  and the  independent  auditors.
Management has the responsibility for the preparation of the Company's financial
statements  and  the  independent  auditors  have  the  responsibility  for  the
examination of those statements.

     Based on the review discussed above and discussions with management and the
independent auditors,  the Audit Committee recommended to the Board of Directors
that the  Company's  audited  financial  statements be included in the Company's
Annual Report on Form 10-K for the year ended  December 31, 2001 for filing with
the Securities and Exchange Commission.

     Audit Fees. The aggregate fees billed for professional services rendered by
the independent  auditors for the audit of the Company's financial statements as
of and for the year ended  December  31,  2001 and the  review of the  financial
statements in the Company's Form 10-Q filings for the year were $135,000.

     All Other  Fees.  The  aggregate  fees billed by the  independent  auditors
during 2001 for  non-audit and  non-information  systems  related  services were
$86,025.   These  services  consisted  of  accounting  compliance  and  research
services, as well as tax consultation, tax compliance and tax research services.
The Audit Committee  considered whether,  and has determined that, the provision
of these  services is compatible  with  maintaining  the  independent  auditors'
independence.  The independent  auditors did not provide  professional  services
during 2001 for the operation of the Company's  information systems or financial
system design and implementation.

                                       13


DISCLAIMER

      This report is being provided to the Company's stockholders solely for
informational purposes. You should not consider this report to be "soliciting
material" or to be "filed" with the SEC. It also is not subject to the SEC's
proxy rules or to the liabilities of Section 18 of the U.S. Security Exchange
Act of 1934. In addition, this report shall not be deemed to be incorporated by
reference into any prior or subsequent filing by the Company under the Federal
securities laws.



                                          AUDIT COMMITTEE
                                          William A. Packer, Chairman
                                          Charles L. Bolling
                                          Miguel Fernandez











                                       14



COMPENSATION COMMITTEE REPORT

     The  Compensation  Committee of the Board of Directors,  which is currently
comprised  of all  non-employee  Directors of the  Company,  determines,  to the
extent not fixed pursuant to the terms of applicable employment agreements,  the
compensation of the Chief Executive Officer, other employee members of the Board
of  Directors,  and all other  executive  employees  whose  annual  compensation
exceeds  $100,000.  The  compensation  levels of such  officers,  directors  and
employees are subject to the approval of the Board of Directors.

     The Compensation Committee,  being responsible for overseeing and approving
executive  compensation  and  grants  of  stock  options,  is in a  position  to
appropriately  balance the current  cash  compensation  considerations  with the
longer-range incentive-oriented growth outlook associated with stock options.

     The  main  objectives  of  the  Company's  compensation  structure  include
rewarding  individuals  for  their  respective  contributions  to the  Company's
performance,  providing executive officers with a stake in the long-term success
of the  Company and  providing  compensation  programs  and  policies  that will
attract,  retain  and  motivate  qualified  executive  personnel.  The  Board of
Directors  and the  Compensation  Committee  place a great deal of importance on
recruiting,   hiring,  retaining  and  motivating  high  quality  personnel  and
recognize  that by offering  executives  employment  agreements,  it can be more
successful  in  recruiting  experienced   executives  from  large,   established
pharmaceutical  companies.  Historically,  the members of the Board of Directors
and the Compensation  Committee have chosen to achieve these objectives  through
salary  increases,  bonuses and periodic  stock  option  grants.  The  Committee
considered each of these factors in approving the  compensation  for Mr. Murphy,
who serves as President and Chief Executive Officer.

     In determining  compensation,  the Compensation Committee considers,  among
other things, the performance of the Company, improvement in financial position,
strategic alliances,  acquisition of products, product registration,  raising of
capital, compensation levels in competing companies, individual contributions to
the  Company  and the  length of  service  with the  Company.  The  Compensation
Committee also surveyed  executive  compensation of similarly situated companies
and retained the services of an independent law firm,  experienced in employment
and compensation  matters, for the purpose of obtaining  independent,  objective
guidance with respect to the Committee's performance of its duties.

     Compensation  through the periodic  grant of Common Stock and stock options
under the Company's stock option plans is intended to coordinate executives' and
stockholders' long-term interests by creating a direct link between a portion of
executive  compensation  and  increases  in the  price of  Common  Stock and the
long-term  success of the Company.  This method of compensation also permits the
Company to preserve its cash resources.

     During  2001  the  Committee  undertook  a  comprehensive   review  of  the
employment agreements that the Company enters into with each of its officers. It
updated the provisions of the agreement and the Company is entering into the new
agreement with each officer as their current agreement expires.

     For the year 2001, Mr. Murphy,  recommended merit increases and base salary
amounts for each officer  other than  himself  based on his  assessment  of each
officer's  individual  performance and  accomplishment of corporate and personal
objectives.  We evaluated Mr. Murphy's recommendations  regarding each officer's
compensation,  taking  into  account  the  officer's  tenure and our  subjective
assessment of individual performance. We considered Mr. Murphy's recommendations
with  respect to merit  increases  and base  salary  amounts.  We  reviewed  the
accomplishments  and performance of such

                                       15


officers and comparative  compensation data from similar or competing  companies
and then approved compensation packages for each of the Company's officers.

     A significant  portion of the direct  compensation of officers  consists of
annual  incentive  bonuses.  Bonus  targets  are  closely  tied  to  performance
measures, at both the corporate level and at individual areas of responsibility.
Mr. Murphy recommended  specific bonuses for all officers other than himself. We
evaluated Mr. Murphy's  recommendations  regarding each officer's bonus,  taking
into account Mr. Murphy's  assessment of each officer's  individual  performance
and  our  subjective  assessment  of  individual  performance,  in  addition  to
accomplishment  of  corporate  objectives.  We then  approved  the bonuses to be
awarded for the calendar year 2001.

     Future  increases  in  executive   compensation  will  be  based  upon  the
satisfaction of pre-established individual objectives,  extraordinary individual
contributions, corporate milestones and financial performance of the Company.

DISCLAIMER

     This report is being  provided  to the  Company's  stockholders  solely for
informational  purposes.  You should not consider this report or the stock price
performance  graph that follows to be  "soliciting  materials"  or to be "filed"
with  the  SEC.  They  are  not  subject  to the  SEC's  proxy  rules  or to the
liabilities  of  Section  18 of the  U.S.  Security  Exchange  Act of  1934.  In
addition,  this  report  and the  performance  graph  shall  not be deemed to be
incorporated  by reference  into any prior or  subsequent  filing by the Company
under the Federal securities laws.



                                          COMPENSATION COMMITTEE
                                          Michael McGovern, Chairman
                                          Charles L. Bolling
                                          Miguel Fernandez
                                          William Packer


                                       16



COMMON STOCK PERFORMANCE

     The graph presented below compares the cumulative total stockholder  return
on the  Company's  Common Stock for the five years ended  December 31, 2001 with
the  cumulative  total  stockholder  return  for such  period  reflected  in the
Standard  and Poor's  (S&P) 500 Stock  Index and in a peer group  index of three
competing  pharmaceutical  companies  (Andrx  Group,  Cima Labs  Inc.  and Noven
Pharmaceuticals,  Inc.)  (the  "New  Peer  Group")  as well as  three  competing
pharmaceutical  companies that were listed in the Company's 2001 proxy statement
(Dura  Pharmaceuticals,  Inc., MacroChem  Coporation and Noven  Pharmaceuticals,
Inc. (the "Old Peer Group"). Dura Pharmaceuticals,  Inc. was not included in the
New Peer Group  because it merged  with  another  company and the peer group was
then  reconstituted to more closely reflect companies that are comparable to the
Company.  The graph (and the  information  relating  to it) was  obtained by the
Company  from S&P.  The  comparative  returns  shown in the graph assume (i) the
investment  of $100 in the  Company's  Common  Stock,  the  common  stock of the
companies  included  in the S&P 500  Stock  Index  and the  common  stock of the
companies  in the New Peer Group and the Old Peer  Group at the market  close on
December 31, 1996 and (ii) the reinvestment of all dividends.


                             [GRAPH APPEARS HERE]










                                       17



                            TOTAL SHAREHOLDER RETURNS
                             (Dividends Reinvested)



                                                                    ANNUAL RETURN PERCENTAGE
                                                                          Years Ending
Company Name / Index                                 Dec 97        Dec 98        Dec 99        Dec 00        Dec 01
--------------------------------------------------------------------------------------------------------------------
                                                                                               
BENTLEY PHARMACEUTICALS                               -9.52        -36.84        312.50         -5.05         73.45
S&P 500 INDEX                                         33.36         28.58         21.04         -9.10        -11.89
NEW PEER GROUP                                        15.72         29.63         95.74        174.61          0.36
OLD PEER GROUP                                        -7.33        -59.36         12.55         78.07        -47.42




                                                                        INDEXED RETURNS
                                   Base                                   Years Ending
                                  Period
Company Name / Index              Dec 96             Dec 97        Dec 98        Dec 99        Dec 00        Dec 01
--------------------------------------------------------------------------------------------------------------------
                                                                                           
BENTLEY PHARMACEUTICALS             100               90.48         57.14        235.71        223.81        388.19
S&P 500 INDEX                       100              133.36        171.48        207.56        188.66        166.24
NEW PEER GROUP                      100              115.72        150.01        293.62        806.31        809.24
OLD PEER GROUP                      100               92.67         37.67         42.39         75.49         39.70





New Peer Group                               Old Peer Group
--------------                               --------------
ANDRX GROUP                                  DURA PHARMACEUTICALS INC
CIMA LABS INC                                MACROCHEM CORP
NOVEN PHARMACEUTICALS INC                    NOVEN PHARMACEUTICALS INC
                                       18



                                  MISCELLANEOUS

VOTING REQUIREMENTS

     Directors  are elected by a  plurality  of the votes cast at the Meeting at
which a quorum is present (Proposal 1).

INDEPENDENT AUDITORS

     The Audit  Committee  of the Board of  Directors  of the  Company  selected
Deloitte & Touche LLP to serve as the  Company's  independent  auditors  for the
year  ended  December  31,  2001  and for the year  ending  December  31,  2002.
Representatives  of  Deloitte  &  Touche  LLP do not plan to be  present  at the
Meeting.

STOCKHOLDER PROPOSALS

     From time to time stockholders may present proposals for consideration at a
meeting,  which may be proper  subjects for inclusion in the proxy statement and
form of proxy  related to that  meeting.  Stockholder  proposals  intended to be
included in the  Company's  proxy  statement  and form of proxy  relating to the
Company's 2003 Annual Meeting of Stockholders must be received by the Company at
its office at 65 Lafayette Road, North Hampton,  New Hampshire 03862 by December
19, 2002. Any such proposals,  as well as any questions relating thereto, should
be directed to the Secretary of the Company at such address.

ADDITIONAL INFORMATION

     The cost of  solicitation  of Proxies,  including  the cost of  reimbursing
banks, brokers and other nominees for forwarding Proxy solicitation  material to
the beneficial owners of shares held of record by them and seeking  instructions
from such beneficial owners,  will be borne by the Company.  The Company has not
engaged a proxy solicitor to solicit proxies;  however, proxies may be solicited
without  extra  compensation  by certain  officers and regular  employees of the
Company. Proxies may be solicited by mail and, if determined to be necessary, by
telephone, telegraph or personal interview.

OTHER MATTERS

     Management  does not intend to bring  before the Meeting any matters  other
than those  specifically  described above and knows of no matters other than the
foregoing to come before the Meeting.  If any other matters or motions  properly
come  before  the  Meeting,  it is the  intention  of the  persons  named in the
accompanying  Proxy to vote such Proxy in accordance with their judgment on such
matters or  motions,  including  any  matters  dealing  with the  conduct of the
Meeting.


                                          By Order of the Board of Directors

                                          MICHAEL D. PRICE
                                          Secretary
North Hampton, NH
April 18, 2002


                                       19


                          BENTLEY PHARMACEUTICALS, INC.
                  ANNUAL MEETING OF STOCKHOLDERS - MAY 22, 2002
               PROXY SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

     The undersigned holder of Common Stock of Bentley Pharmaceuticals,  Inc., a
Delaware corporation (the "Company"),  hereby appoints James R. Murphy,  Michael
D. Price and Jordan A. Horvath and each of them, as proxies for the undersigned,
each with full power of substitution,  for and in the name of the undersigned to
act for the undersigned and to vote, as designated  below,  all of the shares of
stock of the Company that the undersigned is entitled to vote at the 2002 Annual
Meeting of Stockholders of the Company,  to be held on Wednesday,  May 22, 2002,
at 11:00 a.m.,  local time, at the Grand Hyatt New York,  located at Park Avenue
at Grand Central  Station  (42nd  Street),  New York,  New York 10017 and at any
adjournments or postponements thereof.

                  (CONTINUED AND TO BE SIGNED ON REVERSE SIDE)

1. The  election  of Class  III  Directors  until  the 2005  Annual  Meeting  of
Stockholders,  or until  the  election  and  qualification  of their  respective
successors:

|_|    FOR ALL NOMINEES        |_|   WITHHOLD AUTHORITY to vote for all nominees

(INSTRUCTION:  To withhold authority            Nominees:  Miguel Fernandez
for any individual nominee, strike                         James R. Murphy
a line through the nominee's name                          Robert M. Stote, M.D.
on the list at right.)

2. Upon such other  matters as may properly  come before the Annual  Meeting and
any adjournments or postponements thereof. In their discretion,  the proxies are
authorized  to vote upon such other  business  as may  properly  come before the
Annual Meeting and any adjournments or postponements thereof.


THIS PROXY, WHEN PROPERLY EXECUTED,  WILL BE VOTED IN THE MANNER DIRECTED HEREIN
BY THE  UNDERSIGNED  STOCKHOLDER.  IF NO DIRECTION  IS MADE,  THIS PROXY WILL BE
VOTED "FOR" THE ELECTION OF ALL CLASS III DIRECTOR NOMINEES LISTED ABOVE.

                                      -1-


The undersigned hereby acknowledges receipt of (i) the Notice of Annual Meeting,
(ii) the Proxy Statement and (iii) the Company's 2001 Annual Report.

PLEASE  MARK,  SIGN AND DATE  THIS  PROXY  CARD AND  PROMPTLY  RETURN  IT IN THE
ENVELOPE PROVIDED. NO POSTAGE NECESSARY IF MAILED IN THE UNITED STATES.


                                    Dated: ______________________, 2002


                                    --------------------------------------------
                                    Signature


                                    --------------------------------------------
                                    Print Full Name


                                    --------------------------------------------
                                    Signature


                                    --------------------------------------------
                                    Print Full Name


NOTE: Please sign exactly as your name appears hereon and mail it promptly. When
shares are held by joint  tenants,  both should sign.  When signing as attorney,
executor, administrator, trustee or guardian, please give full title as such. If
a  corporation,  please  sign  in full  corporate  name by  president  or  other
authorized  officer.  If a  partnership,  please  sign  in  partnership  name by
authorized person.


                                      -2-