Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
Voya Financial, Inc.
  2. Issuer Name and Ticker or Trading Symbol
KAYNE ANDERSON MIDSTREAM/ENERGY FUND, INC. [KMF]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
230 PARK AVENUE
3. Date of Earliest Transaction (Month/Day/Year)
01/05/2016
(Street)

NEW YORK, NY 10169
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Series B Mandatory Redeemable Preferred Shares 01/05/2016   J(1)   66,667 D $ 25.61 133,333 I (2) By Subsidiary
Series B Mandatory Redeemable Preferred Shares 03/03/2018   J(3)   133,333 D $ 25 0 I (2) By Subsidiary
Series C Mandatory Redeemable Preferred Shares 02/29/2016   J(4)   50,000 D $ 25.75 350,000 I (2) By Subsidiary
Series D Mandatory Redeemable Preferred Shares 08/06/2018   J(5)   800,000 A (5) $ 25 800,000 I (2) By Subsidiary

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Voya Financial, Inc.
230 PARK AVENUE
NEW YORK, NY 10169
    X    
Voya Holdings, Inc.
ONE ORANGE WAY
WINDSOR, CT 06095
    X    
VOYA RETIREMENT INSURANCE & ANNUITY Co
ONE ORANGE WAY
WINDSOR, CT 06095
    X    
VOYA INVESTMENT MANAGEMENT LLC
ONE ORANGE WAY
WINDSOR, CT 06095
    X    

Signatures

 /s/ Jean Weng, SVP & Corporate Secretary, Voya Financial, Inc.   08/08/2018
**Signature of Reporting Person Date

 /s/ Jean Weng, SVP & Assistant Secretary, Voya Holdings Inc.   08/08/2018
**Signature of Reporting Person Date

 /s/ Jean Weng, SVP & Assistant Secretary, Voya Retirement Insurance and Annuity Company   08/08/2018
**Signature of Reporting Person Date

 /s/ Joshua Winchester, VP, Voya Investment Management, LLC   08/08/2018
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) On January 5, 2016, the Issuer redeemed $10,000,000 of its Series B Mandatory Redeemable Preferred Shares.
(2) Most of the securities reported herein are directly beneficially owned by Voya Retirement Insurance and Annuity Company, Security Life of Denver Insurance Company, ReliaStar Life Insurance Company and ReliaStar Life Insurance Company of New York, each a direct or indirect subsidiary of Voya Financial, Inc. and/or Voya Holdings Inc. With respect to the remainder of the securities reported herein, Voya Investment Management, LLC, a subsidiary of Voya Holdings Inc., in its capacity as investment adviser to a third-party owner of such securities, has been delegated certain voting rights pursuant to an investment management contract with such third party, making Voya Investment Management, LLC a beneficial owner of such securities solely for regulatory reporting purposes. Voya Holdings Inc. is a direct subsidiary of Voya Financial, Inc. Voya Financial, Inc. is the indirect beneficial owner of the securities reported herein.
(3) On March 3, 2018, the remaining Series B Mandatory Redeemable Preferred Shares of the Issuer matured.
(4) On February 29, 2016, the Issuer redeemed $5,000,000 of its Series C Mandatory Redeemable Preferred Shares.
(5) The Securities reported herein were terminated and reissued in connection with the Merger of Kayne Anderson Total Return Fund, Inc. (KYE) into KMF. on August 6, 2018. A separate Form 4 will be filed reporting the disposition of the securities terminated under that Issuer. These securities were formerly held as KYE Series C Mandatorily Redeemable Preferred Shares.

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