Ownership Submission
FORM 5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Form 3 Holdings Reported
Form 4 Transactions Reported
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

ANNUAL STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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1. Name and Address of Reporting Person *
Lievense Jefferson
2. Issuer Name and Ticker or Trading Symbol
AMYRIS, INC. [AMRS]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
EVP of Process Development
(Last)
(First)
(Middle)

C/O AMYRIS, INC., 5885 HOLLIS ST., SUITE 100
3. Statement for Issuer's Fiscal Year Ended (Month/Day/Year)
12/31/2011
(Street)


EMERYVILLE, CA 94608
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Reporting
(check applicable line)

_X_ Form Filed by One Reporting Person
___ Form Filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned at end of Issuer's Fiscal Year
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Amount (A) or (D) Price

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 2270 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned at End of Issuer's Fiscal Year
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
(A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy) $ 4.31 02/16/2011   G   50,000   (1)(2) 09/13/2019 Common Stock
50,000
$ 0 0
D
 
Stock Option (Right to Buy) $ 4.31 02/16/2011   G 50,000     (1)(2) 09/13/2019 Common Stock
50,000
$ 0 50,000
I
By the Lievense Revocable Trust (4)
Stock Option (Right to Buy) $ 9.32 02/16/2011   G   30,000   (1)(3) 01/06/2020 Common Stock
30,000
$ 0 0
D
 
Stock Option (Right to Buy) $ 9.32 02/16/2011   G 30,000     (1)(3) 01/06/2020 Common Stock
30,000
$ 0 30,000
I
By the Lievense Revocable Trust (4)

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Lievense Jefferson
C/O AMYRIS, INC.
5885 HOLLIS ST., SUITE 100
EMERYVILLE, CA 94608
      EVP of Process Development  

Signatures

/s/ Jefferson Lievense by Nicholas Khadder, Attorney-in-Fact 02/13/2012
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Immediately exercisable.
(2) The stock option vested as to 1/5th of the total number of shares subject to the option on October 1, 2009, and thereafter vested and shall vest as to 1/60th of the total number of shares subject to the option equal monthly installments.
(3) The stock option vested as to 1/60th of the total number of shares subject to the option on November 27, 2009, and thereafter vested and shall vest as to 1/60th of the total number of shares subject to the option equal monthly installments.
(4) The Reporting Person transferred this option to the Lievense Revocable Trust on February 16, 2011. The Reporting Person is a Trustee of the Lievense Revocable Trust.

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