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                                 UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM N-Q

                   QUARTERLY SCHEDULE OF PORTFOLIO HOLDINGS
		  OF REGISTERED MANAGEMENT INVESTMENT COMPANY



		Investment Company Act file number 811-21409


                   Pioneer Municipal High Income Advantage Trust
               (Exact name of registrant as specified in charter)


                       60 State Street, Boston, MA 02109
              (Address of principal executive offices) (ZIP code)


            Terrence J. Cullen, Pioneer Investment Management, Inc.,
                       60 State Street, Boston, MA 02109
                    (Name and address of agent for service)


Registrant's telephone number, including area code:  (617) 742-7825


Date of fiscal year end:  March 31

Date of reporting period:  June 30, 2010

Form N-Q is to be used by management investment companies, other than small
business investment companies registered on Form N-5 (239.24 and 274.5 of this
chapter), to file reports with the Commission, not later than 60 days after
close of the first and third fiscal quarters, pursuant to Rule 30b1-5 under
the Investment Company Act of 1940 (17 CFR 270.30b1-5).  The Commission may
use the information provided on Form N-Q in its regulatory, disclosure review,
inspection, and policymaking roles.

A registrant is required to disclose the information specified by Form N-Q,
and the Commission will make this information public. A registrant is not
required to respond to the collection of information contained in Form N-Q
unless the Form displays a currently valid Office of Management and Budget
("OMB") control number. Please direct comments concerning the accuracy of the
information collection burden estimate and any suggestions for reducing the
burden to Secretary, Securities and Exchange Commission, 450 Fifth Street, NW,
Washington, DC 20549-0609.  The OMB has reviewed this collection of information
under the clearance requirements of 44 U.S.C. ss. 3507.



ITEM 1. Schedule of Investments.

Pioneer Municipal High Income Advantage Trust
         SCHEDULE OF INVESTMENTS 6/30/10 (unaudited)



Principal
 Amount                                                     Value

         TAX-EXEMPT OBLIGATIONS - 143.9% of Net Assets

         Alabama - 0.7%
2,500,000Huntsville-Redstone Village Special Care Faci $          1,896,625

         Arizona - 3.4%
5,000,000Casa Grande Industrial Development Authority  $          4,987,500
1,521,000Pima County Industrial Development Authority,             1,473,803
2,640,000Pima County Industrial Development Authority,             2,466,974
1,000,000San Luis Facility Development Corp., 7.25%, 5                917,080
                                                       $          9,845,357
         California - 12.3%
3,140,000California State University Revenue, RIB, 12. $          3,232,504
2,425,000California State Various Purpose, 5.75%, 4/1/             2,570,621
8,575,000California State Various Purpose, RIB, 12.752             8,574,057
803,175  California Statewide Communities Development                   79,113
2,680,000Golden State Tobacco Securitization Corp., 6.             3,113,838
2,500,000San Jose California Airport Revenue, 5.0%, 3/             2,470,775
10,500,00University of California, RIB, 13.063%, 5/15/           10,897,740
7,670,000Valley Health System Hospital Revenue, 6.875%             4,205,768
                                                       $        35,144,416
         Colorado - 1.1%
2,850,000Denver Health & Hospital Authority Healthcare $          3,070,704

         Connecticut - 2.7%
7,750,000Connecticut State Development Authority Reven $          7,706,987

         District of Columbia - 3.3%
2,700,000District of Columbia Tobacco Settlement Finan $          2,585,331
6,825,000District of Columbia Tobacco Settlement Finan             6,737,981
                                                       $          9,323,312
         Florida - 3.7%
4,500,000Hillsborough County Industrial Development Authority Pollution Control
Revenue,
            5.5%, 10/1/23                              $          4,588,290
1,980,000Hillsborough County Industrial Development Au             1,928,401
1,000,000Hillsborough County Industrial Development Au             1,135,630
500,000  Miami Beach Health Facilities Authority, 5.37                432,435
2,500,000Miami-Dade County Florida Aviation Revenue, 5             2,541,450
                                                       $        10,626,206
         Georgia - 4.6%
5,210,000Atlanta Georgia Water and Wastewater Revenue, $          5,113,615
1,000,000Clayton County Development Authority Special              1,037,850
900,000  DeKalb County Hospital Authority Revenue, 6.0                899,910
750,000  DeKalb County Hospital Authority Revenue, 6.1                744,308
1,065,000Effingham County Industrial Development Autho             1,064,925
3,360,000Fulton County Residential Care Facilities, 7.             2,531,525
1,650,000Savannah Georgia Economic Development Authori             1,652,937
                                                       $        13,045,070
         Guam - 1.8%
4,500,000Northern Mariana Islands, 6.75%, 10/1/33      $          5,221,035

         Idaho - 1.7%
2,000,000Power County Industrial Development Corp., 6. $          2,011,700
3,000,000Power County Pollution Control Revenue, 5.625             2,999,850
                                                       $          5,011,550
         Illinois - 7.5%
3,000,000Centerpoint Intermodal Center, 7.5%, 6/15/23  $          3,024,810
2,000,000City of Chicago Illinois, 5.5%, 12/1/30                   1,464,080
1,450,000Illinois Finance Authority Revenue, 5.5%, 4/1             1,445,708
1,000,000Illinois Finance Authority Revenue, 6.0%, 11/                778,660
2,000,000Illinois Finance Authority Revenue, 6.0%, 8/1             2,093,900
2,000,000Illinois Finance Authority Revenue, 6.0%, 8/1             2,175,520
2,500,000Illinois Finance Authority Revenue, 6.125%, 1             2,208,250
6,000,000Illinois Finance Authority Revenue, 8.25%, 5/             5,884,740
1,500,000Illinois Health Facilities Authority Revenue,                570,600
2,525,000Southwestern Illinois Development Authority R             1,843,906
                                                       $        21,490,174
         Indiana - 5.8%
250,000   East Chicago Indiana Exempt Facilities Reven $             240,833
10,000,00Indiana State Development Finance Authority R           10,189,800
5,000,000Jasper County Industrial Economic Development             4,540,900
1,995,000Vincennes Industrial Economic Development Rev             1,675,421
                                                       $        16,646,954
         Kentucky - 1.5%
500,000  Kentucky Economic Development Finance Authority Hospital
         System Revenue, 5.7%, 10/1/10                 $             500,055
4,400,000Kentucky Economic Development Finance Authority Hospital
         System Revenue, 5.875%, 10/1/22                           3,909,400
                                                       $          4,409,455
         Louisiana - 6.2%
2,500,000Louisiana Local Government Environmental Faci $          2,578,300
         Authority Revenue, 6.75%, 11/1/32
6,000,000Louisiana Public Facilities Authority Revenue             5,317,320
750,000  Opelousas Louisiana General Hospital Authorit                759,135
9,415,000Tobacco Settlement Financing Corp., 5.875%, 5             9,190,641
                                                       $        17,845,396
         Maryland - 0.9%
460,000  Maryland Health & Higher Educational Faciliti $             380,379
1,250,000Maryland Health & Higher Educational Faciliti                894,363
1,250,000Maryland Health & Higher Educational Faciliti             1,185,200
                                                       $          2,459,942
         Massachusetts - 7.6%
830,000  Massachusetts Development Finance Agency, 5.2 $             737,140
5,000,000Massachusetts Development Finance Agency, 5.7             5,523,650
1,930,000Massachusetts Development Finance Agency, 7.1             1,766,008
2,195,000Massachusetts Health & Educational Facilities             1,920,054
1,000,000Massachusetts Health & Educational Facilities             1,126,140
10,760,00Massachusetts Housing Finance Agency, 5.35%,            10,541,787
                                                       $        21,614,779
         Michigan - 3.5%
1,500,000Delta County Michigan Economic Development Co $          1,652,700
500,000  Flint Michigan Hospital Building Authority Re                505,700
3,000,000Macomb County Hospital Finance Authority Reve             3,483,570
745,000  Michigan Public Educational Facilities Author                680,252
4,130,000Michigan State Hospital Finance Authority Rev             3,622,712
3,405,000Wayne Charter Escrow, 0.0%, 12/1/15
                                                       $          9,944,934
         Missouri - 0.9%
1,500,000St. Louis Industrial Development Authority Re $             480,540
6,640,000St. Louis Industrial Development Authority Re             2,124,070
                                                       $          2,604,610
         Montana - 0.5%
2,445,000Hardin Increment Industrial Infrastructure De $          1,385,435
1,000,000Two Rivers Authority, Inc., Project Revenue,                 174,950
                                                       $          1,560,385
         Nevada - 2.1%
1,500,000Henderson Nevada Health Care Facilities Reven $          1,539,645
1,600,000Nevada State Department of Business & Industr                  16,000
1,000,000Nevada State Department of Business & Industr                  10,000
1,320,000Nevada State Department of Business & Industr                  13,200
5,000,000Reno Nevada Hospital Revenue, 5.25%, 6/1/41               4,579,800
                                                       $          6,158,645
         New Hampshire - 0.4%
1,125,000New Hampshire Health & Educational Facilities $          1,067,557

         New Jersey - 11.9%
2,500,000Burlington County New Jersey Bridge Commissio $          2,158,775
13,000,00New Jersey Economic Development Authority Rev           11,951,290
3,500,000New Jersey State Turnpike Authority, RIB, 13.             4,882,430
10,375,00New Jersey Transportation Trust Fund Authorit             4,284,875
1,000,000Tobacco Settlement Financing Corp., 6.25%, 6/             1,155,470
3,250,000Tobacco Settlement Financing Corp., 6.75%, 6/             3,802,045
5,000,000Tobacco Settlement Financing Corp., 7.0%, 6/1             5,883,650
                                                       $        34,118,535
         New York - 7.9%
1,800,000Dutchess County Industrial Development Agency $          1,796,148
3,000,000Nassau County New York Industrial Development             2,949,330
5,000,000New York City Industrial Development Agency,              3,705,400
3,950,000New York City Industrial Development Agency,              3,944,154
2,000,000New York State Dormitory Authority Revenue, 6             1,992,000
5,000,000New York State Environmental Facilities Corp.             5,125,500
3,000,000Ulster County New York Industrial Development             2,718,900
500,000  Ulster County New York Industrial Development                409,965
                                                       $        22,641,397
         North Carolina - 2.1%
6,000,000Charlotte North Carolina Special Facilities R $          6,003,720

         Ohio - 1.7%
2,375,000Belmont County Health System Revenue, 5.7%, 1 $          1,726,554
1,000,000Belmont County Health System Revenue, 5.8%, 1                727,460
3,000,000Cleveland Airport Special Revenue, 5.375%, 9/             2,487,600
                                                       $          4,941,614
         Oklahoma - 2.8%
1,500,000Jackson County Memorial Hospital Authority Re $          1,501,050
2,220,000Tulsa Municipal Airport Trust Revenue, 6.25%,             2,026,616
1,500,000Tulsa Municipal Airport Trust Revenue, 7.35%,             1,499,850
3,000,000Tulsa Municipal Airport Trust Revenue, 7.75%,             3,015,210
                                                       $          8,042,726
         Oregon - 1.1%
3,000,000Oregon State Facilities Authority Revenue, 5. $          3,021,030

         Pennsylvania - 8.8%
3,000,000Allegheny County Hospital Development Authori $          3,159,690
500,000  Allegheny County Hospital Development Authori                526,615
3,600,000Columbia County Hospital Authority Revenue, 5             3,222,036
830,000  Hazleton Health Services Authority Hospital R                829,992
1,405,000Montgomery County Higher Education & Health Authority
         Hospital Revenue, 6.6%, 7/1/10                            1,405,197
1,430,000Pennsylvania Economic Development Financing Authority
         Revenue, 5.125%, 6/1/18                                   1,284,941
2,330,000Pennsylvania Economic Development Financing A             2,292,137
5,000,000Pennsylvania Economic Development Financing A             4,315,100
5,000,000Philadelphia Hospitals & Higher Education Fac             4,079,050
2,005,000Scranton-Lackawanna Health & Welfare Authorit             1,979,476
2,245,000Scranton-Lackawanna Health & Welfare Authorit             2,189,953
                                                       $        25,284,187
         Rhode Island - 3.2%
1,385,000Central Falls Rhode Island Detention Faciliti $          1,186,405
8,285,000Tobacco Settlement Financing Corp., 6.25%, 6/             7,847,801
                                                       $          9,034,206
         South Carolina - 6.2%
1,500,000Connector 2000 Association, Inc., Toll Road R $             303,750
7,140,000South Carolina Jobs Economic Development Auth             8,244,986
860,000  South Carolina Jobs Economic Development Auth                998,778
3,000,000South Carolina Jobs Economic Development Auth             3,112,800
4,400,000Tobacco Settlement Revenue Management, 6.375%             5,231,204
                                                       $        17,891,518
         Tennessee - 3.8%
1,000,000Johnson City Health & Educational Facilities  $          1,133,710
7,000,000Knox County Health Educational & Housing Facilities Board
         Hospital Revenue, 6.5%, 4/15/31                           7,450,660
2,400,000Sullivan County Health Educational and Housing Facilities Board
         Hospital Revenue, 5.25%, 9/1/36                           2,193,120
                                                       $        10,777,490
         Texas  - 16.4%
2,827,399Gulf Coast Industrial Development Authority,  $             278,499
10,000,00Houston Texas Airport System Special Faciliti             9,729,200
845,000  IAH Public Facility Corp., Project Revenue Bo                779,791
1,000,000IAH Public Facility Corp., Project Revenue Bo                831,290
1,350,000IAH Public Facility Corp., Project Revenue Bo             1,083,524
2,750,000Lower Colorado River Authority, 5.0%, 5/15/31             2,777,775
845,000  Lubbock Health Facilities Development Corp.,                 813,346
2,000,000Lubbock Health Facilities Development Corp.,              1,846,560
7,750,000Matagorda County Navigation District Number 1             7,677,150
9,750,000North Texas Tollway Authority Revenue, 5.75%,           10,246,372
1,711,000Panhandle Regional Housing Finance Corp. Multifamily Housing
         Revenue, 6.6%, 7/20/31                                    1,814,533
1,000,000Richardson Hospital Authority Revenue, 6.0%,                 948,500
1,000,000Tarrant County Cultural Education Facilities                 994,090
1,500,000Tarrant County Cultural Education Facilities              1,497,210
1,000,000Texas Midwest Public Facility Corp. Revenue,              1,034,700
4,700,000Tomball Hospital Authority, 6.0%, 7/1/25                  4,568,870
                                                       $        46,921,410
         Utah  - 0.5%
1,600,000Spanish Fork Charter School Revenue, 5.7%, 11 $          1,295,760

         Virginia  - 0.8%
2,000,000Washington County Industrial Development Auth $          2,274,700

         Washington - 3.1%
1,155,000Tobacco Settlement Authority Revenue, 6.5%, 6 $          1,180,202
2,000,000Washington State Health Care Facilities Autho             2,038,500
2,000,000Washington State Health Care Facilities Autho             2,045,900
5,000,000Washington State Housing Finance Commission Nonprofit
         Revenue Bonds, 5.625%, 1/1/27                             3,740,550
                                                       $          9,005,152
         Wisconsin  - 1.4%
2,900,000Aztalan Wisconsin Exempt Facilities Revenue,  $             391,500
1,000,000Wisconsin State Health & Educational Faciliti             1,006,360
1,000,000Wisconsin State Health & Educational Faciliti                972,190
1,500,000Wisconsin State Health & Educational Faciliti             1,622,025
                                                       $          3,992,075
         TOTAL TAX-EXEMPT OBLIGATIONS
         (Cost $405,289,753)                           $      411,939,613

         MUNICIPAL COLLATERALIZED DEBT OBLIGATION - 3.4% of Net Assets
13,000,00Non-Profit Preferred Funding Trust I, Series  $          9,638,070
         TOTAL MUNICIPAL COLLATERALIZED DEBT OBLIGATION
         (Cost $13,000,000)                            $          9,638,070

 Shares  COMMON STOCK - 0.5% of Net Assets
109,889  Delta Airlines, Inc.                          $          1,291,196
         TOTAL COMMON STOCK
         (Cost $3,210,349)                             $          1,291,196

         TAX-EXEMPT MONEY MARKET MUTUAL FUND - 1.0% of Net Assets
  3,000,0BlackRock Liquidity Funds MuniFund Portfolio  $          3,000,000
         TOTAL TAX-EXEMPT MONEY MARKET MUTUAL FUND
         (Cost $3,000,000)                             $          3,000,000

         TOTAL INVESTMENTS IN SECURITIES - 148.8%
         (Cost $424,500,102) (i)(j)                    $      425,868,879
         OTHER ASSETS AND LIABILITIES  3.6%            $        10,327,030
         PREFERRED SHARES AT REDEMPTION VALUE,
         INCLUDING DIVIDENDS PAYABLE - (52.4)%         $     (150,005,046)
         NET ASSETS APPLICABLE TO COMMON SHAREOWNERS - $      286,190,863

 (144A)  Security is exempt from registration under Rule 144A of the
         Securities Act of 1933.
         Such securities may be resold normally to qualified
         institutional buyers in a transaction
         exempt from registration.  At June 30, 2010,
         the value of these securities
         amounted to $35,761,246, or 12.5% of total net
         assets applicable to
         common shareowners.

    RIB  Residual Interest Bonds.

     NR  Security not rated by S&P or Moody's.

     +   Prerefunded bonds have been collateralized by U.S. Treasury or U.S.
         Government Agency securities which are held in escrow to pay interest
         and principal on the tax exempt issue and to retire the bonds in full
at the
         earliest refunding date.

    (a)  The interest rate is subject to change periodically and inversely based
          upon prevailing market rates.  The rate shown is the coupon rate
         at June 30, 2010.

    (b)  Security is in default and is non-income producing.

    (c)  The interest rate is subject to change periodically.
          The interest rate shown is the coupon rate at June 30, 2010.

    (d)  Non-income producing.

    (e)  Security is valued using fair value methods (other than prices
         supplied by independent pricing services).

    (f)  Debt obligation initially issued at one coupon rate which
         converts to a higher coupon rate at a specific date.
         The rate shown is the coupon rate at June 30, 2010.

    (g)  Indicates a security that has been deemed illiquid.
         The aggregate cost of illiquid securities is $16,341,938.  The
aggregate value is
         $10,042,770, or 3.5% of the total net assets applied to common
shareowners.

    (h)  Escrow to maturity.

    (i)  The concentration of investments by type of obligation/market sector
is as follows:
         Insured
         AGM                                                   8.2 %
         AMBAC                                                 1.9
         MBIA                                                  1.0
         Q-SBLF                                                0.2
         Revenue Bonds:
         Health Revenue                                       35.5
         Airport Revenue                                      11.4
         Tobacco Revenue                                      11.1
         Other Revenue                                         8.0
         Pollution Control Revenue                             6.6
         Development Revenue                                   5.1
         Housing Revenue                                       2.9
         Facilities Revenue                                    2.5
         Transportation Revenue                                2.5
         Water Revenue                                         1.2
         Power Revenue                                         1.1
         Education Revenue                                     0.8
         Utilities Revenue*                                    0.0
                                                              100.0%
         Amount is less than 0.1%

    (j)  At June 30, 2010, the net unrealized gain on investments
         based on cost for federal income tax purposes
         of $419,754,512 was as follows:

              Aggregate gross unrealized gain for all investments in which
              there is an excess of value over tax cos $        39,904,297

              Aggregate gross unrealized loss for all investments in which
              there is an excess of tax cost over valu          (33,789,930)
              Net unrealized gain                      $          6,114,367

         For financial reporting purposes net unrealized gain on investments was
         $1,368,777 and cost of investments aggregated $424,500,102.

         Purchases and sales of securities (excluding temporary cash
         investments)
         for the period ended June 30, 2010
         aggregated $10,694,210 and $8,042,380, respectively.

Various inputs are used in determining the value of the
                 Fund's investments.  These inputs are summarized in the
                 three broad levels listed below.
                 Highest priority is given to Level 1 inputs and lowest
                     priority is given to Level 3.
                 Level 1 - quoted prices in active markets for identical
                    securities
                 Level 2 - other significant observable inputs (including
                     quoted prices for similar securities, interest rates,
                     prepayment speeds, credit risk, etc.)
                 Level 3 - significant unobservable inputs (including the
                     Fund's own assumptions in determining fair value of
                     investments)

                 The following is a summary of the inputs used as of June
                 30, 2010, in valuing the Fund's assets:
                                Level 1     Level 2   Level 3     Total
Tax exempt obligations    	   $0    $411,939,613  $0     $411,939,613
Municipal collateralized            0       9,368,070   0        9,368,070
Common Stock                1,291,196           0       0        1,291,196
Tax exempt money market     3,000,000           0       0        3,000,000
Total                      $4,291,196    $421,307,683  $0     $425,598,879

Following is a reconciliation of assets valued using
significant unobservable inputs (Level 3):

                                                           Tax-Exempt
                                                           Obligation
                                                           Michigan
Balance as of 3/31/10                                    	$0
Realized gain (loss)                                             0
Change in unrealized gain (loss)                                 0
Net purchases (sales)                                            0
Transfers in and out of level 3
Balance as of 6/30/10                                            $0



ITEM 2. CONTROLS AND PROCEDURES.

(a) Disclose the conclusions of the registrant's principal executive
and principal financial officers, or persons performing similar functions,
regarding the effectiveness of the registrant's disclosure
controls and procedures (as defined in Rule 30a-3(c) under the Act (17 CFR
270.30a-3(c))) as of a date within 90 days of the filing date of the report
that includes the disclosure required by this paragraph, based on the
evaluation of these controls and procedures required by Rule 30a-3(b)
under the Act (17 CFR 270.30a-3(b))) and Rule 13a-15(b) or 15d-15(b)
under the Exchange Act (17 CFR 240.13a-15(b) or 240.15d-15(b)).

The registrant's principal executive officer and principal financial officer
have concluded that the registrant's disclosure controls and procedures are
effective based on their evaluation of these controls and procedures as of
a date within 90 days of the filing date of this report.

(b) Disclose any change in the registrant's internal controls over financial
reporting (as defined in Rule 30a-3(d) under the Act (17 CFR 270.30a-3(d))
that occurred during the registrant's last fiscal quarter that has materially
affected, or is reasonably likely to materially affect, the registrant's
internal control over financial reporting.

There were no significant changes in the registrant's internal control over
financial reporting that occurred during the second fiscal quarter of the
period covered by this report that have materially affected, or are
reasonably likely to materially affect, the registrant's internal control
over financial reporting.



ITEM 3. EXHIBITS.

(a) A separate certification for each principal executive officer and principal
financial officer of the registrant as required by Rule 30a-2(a) under the Act
(17 CFR 270.30a-2(a)).

Filed herewith.






                                   SIGNATURES

                          [See General Instruction F]


Pursuant to the requirements of the Securities Exchange Act of 1934 and the
Investment Company Act of 1940, the registrant has duly caused this report to be
signed on its behalf by the undersigned, thereunto duly authorized.


(Registrant) Pioneer Municipal High Income Advantage Trust

By (Signature and Title)* /s/ John F. Cogan, Jr.
John F. Cogan, Jr, President

Date August 27, 2010


Pursuant to the requirements of the Securities Exchange Act of 1934 and the
Investment Company Act of 1940, this report has been signed below by the
following persons on behalf of the registrant and in the capacities and on the
dates indicated.


By (Signature and Title)* /s/ John F. Cogan, Jr.
John F. Cogan, Jr., President

Date August 27, 2010



By (Signature and Title)* /s/ Mark Bradley
Mark Bradley, Treasurer

Date August 27, 2010

* Print the name and title of each signing officer under his or her signature.