Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
Redpoint Ventures III, LLC
  2. Issuer Name and Ticker or Trading Symbol
2U, Inc. [TWOU]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
3000 SAND HILL ROAD, BUILDING 2, SUITE 290
3. Date of Earliest Transaction (Month/Day/Year)
04/02/2014
(Street)

MENLO PARK, CA 94025
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 04/02/2014   C   7,234,906 (1) A (2) 7,234,906 I By funds (3) (4)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 1474 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Series A Preferred Stock (2) 04/02/2014   C     4,728,505   (2)   (2) Common Stock 4,728,505 $ 0 0 I By funds (4) (5)
Series B Preferred Stock (2) 04/02/2014   C     1,185,498   (2)   (2) Common Stock 1,185,498 $ 0 0 I By funds (4) (6)
Series C Preferred Stock (2) 04/02/2014   C     681,075   (2)   (2) Common Stock 681,075 $ 0 0 I By funds (4) (7)
Series D Preferred Stock (2) 04/02/2014   C     639,828   (2)   (2) Common Stock 639,828 $ 0 0 I By funds (4) (8)

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Redpoint Ventures III, LLC
3000 SAND HILL ROAD
BUILDING 2, SUITE 290
MENLO PARK, CA 94025
    X    
REDPOINT VENTURES III LP
3000 SAND HILL ROAD
BUILDING 2, SUITE 290
MENLO PARK, CA 94025
    X    
Redpoint Associates III, LLC
3000 SAND HILL ROAD
BUILDING 2, SUITE 290
MENLO PARK, CA 94025
    X    

Signatures

 /s/ Timothy M. Haley, Managing Director   04/02/2014
**Signature of Reporting Person Date

 By: Redpoint Ventures III, LLC, its general partner, By: /s/ Timothy M. Haley, Managing Director   04/02/2014
**Signature of Reporting Person Date

 By: /s/ Timothy M. Haley, Manager   04/02/2014
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The total represents shares received upon conversion of shares of Series A, Series B, Series C and Series D convertible preferred stock.
(2) Effective upon the closing of the issuer's initial public offering of its common stock, each share of convertible preferred stock automatically converted into one share of common stock. The convertible preferred stock had no expiration date.
(3) The total consists of 6,963,598 shares held by Redpoint Ventures III, L.P. ("Redpoint Ventures") and 271,308 shares held by Redpoint Associates III, LLC ("Redpoint Associates").
(4) The shares held by Redpoint Ventures are indirectly held by Redpoint Ventures III, LLC ("RV III LLC"), the general partner of Redpoint Ventures. Redpoint Associates is under common control with RV III LLC. As such, RV III LLC has voting and investment control over the shares owned by Redpoint Ventures and Redpoint Associates, and may be deemed to beneficially own the shares held by Redpoint Ventures and Redpoint Associates. RV III LLC owns no securities of the issuer directly. RV III LLC disclaims beneficial ownership of the shares reported herein, except to the extent of its pecuniary interest therein.
(5) Consisted of 4,551,186 shares held by Redpoint Ventures and 177,319 shares held by Redpoint Associates.
(6) Consisted of 1,141,042 shares held by Redpoint Ventures and 44,456 shares held by Redpoint Associates.
(7) Consisted of 655,535 shares held by Redpoint Ventures and 25,540 shares held by Redpoint Associates.
(8) Consisted of 615,835 shares held by Redpoint Ventures and 23,993 shares held by Redpoint Associates.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.