UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, DC 20549


                                    FORM 8-K


                             CURRENT REPORT PURSUANT
                          TO SECTION 13 OR 15(d) OF THE
                         SECURITIES EXCHANGE ACT OF 1934


     Date of report (Date of earliest event reported)      August 10, 2005
                                                     ---------------------------

                          IR BioSciences Holdings, Inc.
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             (Exact Name of Registrant as Specified in Its Charter)

                                    Delaware
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                 (State or Other Jurisdiction of Incorporation)

          033-05384                                       13-3301899
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  (Commission File Number)                   (IRS Employer Identification No.)


4021 North 75th Street, Suite 201, Scottsdale, Arizona              85251
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   (Address of Principal Executive Offices)                       (Zip Code)

                                 (480) 922-3926
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              (Registrant's Telephone Number, Including Area Code)


          (Former Name or Former Address, if Changed Since Last Report)

     Check the  appropriate  box below if the Form 8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

     |_| Written  communications  pursuant to Rule 425 under the  Securities Act
(17 CFR 230.425)

     |_| Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17
CFR 240.14a-12)

     |_|  Pre-commencement  communications  pursuant to Rule 14d-2(b)  under the
Exchange Act (17 CFR 240.14d-2(b))

     |_|  Pre-commencement  communications  pursuant to Rule 13e-4(c)  under the
Exchange Act (17 CFR 240.13e-4(c))






ITEM 1.01.  ENTRY INTO A MATERIAL DEFINITIVE AGREEMENT.

     On August 10,  2005,  IR  BioSciences  Holdings,  Inc.  (the  "Registrant")
entered into a new employment  agreement with its President and Chief  Executive
Officer,  Michael K. Wilhelm. The employment agreement calls for a salary at the
rate of $275,000 per annum. The salary will be subject to adjustment of at least
10% per year at the end of each year. The  Registrant  also agreed to defend and
indemnify,  to the fullest extent permitted by the  Registrant's  certificate of
incorporation  and bylaws and the Delaware General  Corporation Law, Mr. Wilhelm
and hold him harmless  against any liability  that he incurs within the scope of
his  employment  under  the  agreement.  The  agreement  also  provides  for the
following various bonus incentives:

     i) A  target  incentive  bonus  in  cash  and/or  stock  if the  Registrant
consummates a transaction with any unaffiliated third party such as an equity or
debt  financing,  acquisition,  merger , strategic  partnership or other similar
transaction.

     ii) A one time  grant of an  option  to  purchase  2,000,000  shares of the
Registrant's  common  stock at an exercise  price equal to the fair market value
per share on the date option is granted.


In connection with Mr. Wilhelm's new employment  agreement,  the Registrant also
entered into a Change of Control Agreement and a Severance Agreement with him on
August 10, 2005.


Under the  Change of Control  Agreement,  Mr.  Wilhelm  shall be  entitled  to a
continuation  of  his  base  salary  for a  period  of 18  months  following  an
Involuntary  Termination,  which means,  at any time within that period which is
one-year from the change of control date (including such date),  the termination
of the employment of Mr. Wilhelm (i) by the Registrant without Cause or (ii) due
to Constructive Termination,  as such terms are defined in the Change of Control
Agreement.  Further, in the event of an Involuntary  Termination,  the agreement
provides that the  Registrant  shall pay Mr.  Wilhelm a lump sum amount in cash,
equal  to the  sum of (i) any  unpaid  incentive  compensation  which  has  been
allocated  or  awarded  to Mr.  Wilhelm  for a  completed  fiscal  year or other
measuring period preceding the date of Involuntary  Termination under any annual
or  long-term   incentive  plan  and  which,  as  of  the  date  of  Involuntary
Termination,  is contingent only upon the continued employment of Mr. Wilhelm to
a  subsequent  date,  and (ii) a pro  rata  portion  to the date of  Involuntary
Termination  of the aggregate  value of all  contingent  incentive  compensation
awards to Mr.  Wilhelm  for all then  uncompleted  periods  under any such plan.
Further,  100% of the unvested portion of each outstanding  stock option granted
to Mr. Wilhelm shall be accelerated so that they become immediately  exercisable
upon the date of Involuntary Termination.

Under the Severance  Agreement,  Mr. Wilhelm shall be entitled to a continuation
of  his  base  salary  for  a  period  of 18  months  following  an  Involuntary
Termination, which means the termination of the employment of Mr. Wilhelm (i) by
the Registrant  without Cause or (ii) due to Constructive  Termination,  as such
terms  are  defined  in the  Severance  Agreement.  Further,  in the event of an
Involuntary  Termination,  the agreement  provides that the Registrant shall pay
Mr.  Wilhelm an amount  equal to the amount of executive  incentive  pay (bonus)


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that he would have  received for the year in which the  Involuntary  Termination
occurred had he met one hundred  percent (100%) of the target for such incentive
pay.  Also,  under  this  agreement,  100%  of  the  unvested  portion  of  each
outstanding  stock option  granted to Mr.  Wilhelm shall be  accelerated so that
they become immediately exercisable upon the date of Involuntary Termination.



                                   SIGNATURES

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.




                                        IR BIOSCIENCES HOLDINGS, INC.


 Date: August 16, 2005

                                         By:    /s/ John N. Fermanis
                                            ------------------------------------
                                         Name:  John N. Fermanis
                                         Title: Chief Financial Officer








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